AC T00497
XX
ID T00497
XX
DT 15.10.1992 (created); ewi.
DT 19.10.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA PRDII-BF1-isoform1
XX
SY HIV-EP1; HIVEP1; human immunodeficiency virus type I enhancer binding protein 1; Major histocompatibility complex binding protein 1; MBP-1 (1); MHC-binding protein 1; positive regulatory domain II-binding factor 1; PRDII-BF1; Zinc finger protein 40; ZNF40.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G003051 HIVEP1; HGNC: HIVEP1.
XX
CL C0001; CH; 2.3.4.5.1.1.
XX
SZ 2717 AA; 297.2 kDa (cDNA) (calc.).
XX
SQ MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKEILQAGVKGTSESLKGVKRKKIVAENHLK
SQ KIPKSPLRNPLQAKHKQNTEESSFAVLHSASESHKKQNYIPVKNGKQFTKQNGETPGIIA
SQ EASKSEESVSPKKPLFLQQPSELRRWRSEGADPAKFSDLDEQCDSSSLSSKTRTDNSECI
SQ SSHCGTTSPSYTNTAFDVLLKAMEPELSTLSQKGSPCAIKTEKLRPNKTARSPPKLKNSS
SQ MDAPNQTSQELVAESQSSCTSYTVHMSAAQKNEQGAMQSASHLYHQHEHFVPKSNQHNQQ
SQ LPGCSGFTGSLTNLQNQENAKLEQVYNIAVTSSVGLTSPSSRSQVTPQNQQMDSASPLSI
SQ SPANSTQSPPMPIYNSTHVASVVNQSVEQMCNLLLKDQKPKKQGKYICEYCNRACAKPSV
SQ LLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPDAGGLFLSHESP
SQ KALSIHSDVEDSGESEEEGATDERQHDLGAMELQNVHIIKRMSNAETLLKSSFTPSSPEN
SQ VIGDFLLQDRSAESQAVTELPKVVVHHVTVSPLRTDSPKAMDPKPELSSAQKQKDLQVTN
SQ VQPLSANMSQGGVSRLETNENSHQKGDMNPLEGKQDSHVGTVHAQLQRQQATDYSQEQQG
SQ KLLSPRSLGSTDSGYFSRSESADQTVSPPTPFARRFPAQNKTLEGVTDPLQLLSPRQHPL
SQ LCHREKALLLPGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSID
SQ SPKSYIFKDSFQFDLKPVGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNS
SQ MPTTGYSAVPANIIPPPHPLRGSQSFDDKIGAFYDDVFVSGPNAPVPQSGHPRTLVRQAA
SQ IEDSSANESHVLGTGQSLDESHQGCHAAGEAMSVRSKALAQGPHIEKKKSHQGRGTMFEC
SQ ETCRNRYRKLENFENHKKFYCSELHGPKTKVAMREPEHSPVPGGLQPQILHYRVAGSSGI
SQ WEQTPQIRKRRKMKSVGDDEELQQNESGTSPKSSEGLQFQNALGCNPSLPKHSVTIRSDQ
SQ QHKNIQLQNSHIHLVARGPEQTMDPKLSTIMEQQISSAAQDKIELQRHGTGISVIQHTNS
SQ LSRPNSFDKPEPFERASPVSFQELNRTGNSGSLKVIGISQEESHPSRDGSHPHQLALSDA
SQ LRGELQESSRKSPSERHVLGQPSRLIRQHNIQVPEILVTEEPDRDLEAQCHDQEKSEKFS
SQ WPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFDSTLSRSLSRESSLSHTSSFSAS
SQ LDIEDVSKTEASPKIDFLNKAEFLMIPAGLNTLNVPGCHREMRRTASEQINCTQTSMEVS
SQ DLRSKSFDCGSITPPQTTPLTELQPPSSPSRVGVTGHVPLLERRRGPLVRQISLGIAPDS
SQ HLSPVHPTSFQNTALPSVNAVPYQGPQLTSTSLAEFSANTLHSQTQVKDLQAETSNSSST
SQ NVFPVQQLCDINLLNQIHAPPSHQSTQLSLQVSTQGSKPDKNSVLSGSSKSEDCFAPKYQ
SQ LHCQVFTSGPSCSSNPVHSLPNQVISDPVGTDHCVTSATLPTKLIDSMSNSHPLLPPELR
SQ PLGSQVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDLPNQPICQTNHSVVPISE
SQ EQNSVPTLQKGHQNALPNPEKEFLCENVFSEMSQNSSLSESLPITQKISVGRLSPQQESS
SQ ASSKRMLSPANSLDIAMEKHQKRAKDENGAVCATDVRPLEALSSRVNEASKQKKPILVRQ
SQ VCTTEPLDGVMLEKDVFSQPEISNEAVNLTNVLPADNSSTGCSKFVVIEPISELQEFENI
SQ KSSTSLTLTVRSSPAPSENTHLSPLKCTDNNQERKSPGVKNQGDKVNIQEQSQRPVTSLS
SQ LFNIKDTQQLAFPSLKTTTNFTWCYLLRQKSLHLPQKDQKTSAYTDWTVSASNPNPLGLP
SQ TKVALALLNSKQNTGKSLYCQAITTHSKSDLLVYSSKWKSSLSKRALGNQKSTVVEFSNK
SQ DASEINSEQDKENSLIKSEPRRIKIFDGGYKSNEEYVYIRGRGRGKYICEECGIRCKKPS
SQ MLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLGISVGLIDEQDTEE
SQ SDEKQRFSYERSGYDLEESDGPDEDDNENEDDDEDSQAESVLSATPSVTASPQHLPSRSS
SQ LQDPVSTDEDVRITDCFSGVHTDPMDVLPRALLTRMTVLSTAQSDYNRKTLSPGKARQRA
SQ ARDENDTIPSVDTSRSPCHQMSVDYPESEEILRSSMAGKAVAITQSPSSVRLPPAAAEHS
SQ PQTAAGMPSVASPHPDPQEQKQQITLQPTPGLPSPHTHLFSHLPLHSQQQSRTPYNMVPV
SQ GGIHVVPAGLTYSTFVPLQAGPVQLTIPAVSVVHRTLGTHRNTVTEVSGTTNPAGVAELS
SQ SVVPCIPIGQIRVPGLQNLSTPGLQSLPSLSMETVNIVGLANTNMAPQVHPPGLALNAVG
SQ LQVLTANPSSQSSPAPQAHIPGLQILNIALPTLIPSVSQVAVDAQGAPEMPASQSKACET
SQ QPKQTSVASANQVSRTESPQGLPTVQRENAKKVLNPPAPAGDHARLDGLSKMDTEKAASA
SQ NHVKPKPELTSIQGQPASTSQPLLKAHSEVFTKPSGQQTLSPDRQVPRPTGLPRRQPTVH
SQ FSDVSSDDDEDRLVIAT
XX
SC Swiss-Prot#P15822-1
XX
FT 406 428 
PF00096; zf-C2H2.
FT 406 428 
SM00355; c2h2final6.
FT 406 433 
PS50157; ZINC_FINGER_C2H2_2.
FT 434 456 
PF00096; zf-C2H2.
FT 434 456 
SM00355; c2h2final6.
FT 434 457 
PS50157; ZINC_FINGER_C2H2_2.
FT 958 985 
SM00355; c2h2final6.
FT 2087 2109 
PF00096; zf-C2H2.
FT 2087 2109 
SM00355; c2h2final6.
FT 2087 2114 
PS50157; ZINC_FINGER_C2H2_2.
FT 2115 2139 PF00096; zf-C2H2.
FT 2115 2139 SM00355; c2h2final6.
FT 2115 2140 PS50157; ZINC_FINGER_C2H2_2.
XX
SF 2+1+2 zinc finger motifs;
SF acidic region;
SF NMR of the second zinc finger;
XX
CP B cells.
XX
BS R00699.
BS R01745.
BS R01746.
BS R00928.
BS R02199.
BS R01059.
BS R01060.
XX
DR TRANSPATH: MO000046005.
DR EMBL: X51435; HSZFPBF1.
DR UniProtKB: P15822-1;
XX
RN [1]; RE0000024.
RX PUBMED: 2248949.
RA Omichinski J. G., Clore G. M., Appella E., Sakaguchi K., Gronenborn A. M.
RT High-resolution three-dimensional structure of a single zinc finger from a human enhancer binding protein in solution
RL Biochemistry 29:9324-9334 (1990).
RN [2]; RE0000610.
RX PUBMED: 2106471.
RA Fan C.-M., Maniatis T.
RT A DNA-binding protein containing two widely separated zinc finger motifs that recognize the same DNA sequence
RL Genes Dev. 4:29-42 (1990).
RN [3]; RE0000974.
RX PUBMED: 2504707.
RA Maekawa T., Sakura H., Sudo T., Ishii S.
RT Putative metal finger structure of the human immunodeficiency virus type 1 enhancer binding protein HIV-EP1
RL J. Biol. Chem. 264:14591-14593 (1989).
RN [4]; RE0001280.
RX PUBMED: 2108316.
RA Baldwin jr A. S., LeClair K. P., Singh H., Sharp P. A.
RT A large protein containing zinc finger domains binds to related sequence elements in the enhancers of the class I major histocompatibility complex and kappa immunoglobulin genes
RL Mol. Cell. Biol. 10:1406-1414 (1990).
RN [5]; RE0002491.
RX PUBMED: 2247438.
RA Rustgi A. K., van't Veer L., Bernards R.
RT Two genes encode factors with NF-kappaB- and H2TF1-like DNA-binding properties
RL Proc. Natl. Acad. Sci. USA 87:8707-8710 (1990).
XX
//