AC T00920
XX
ID T00920
XX
DT 03.11.1992 (created); ewi.
CO Copyright (C), QIAGEN.
XX
FA Zfh-2
XX
SY Zfh-2; Zinc-finger homeodomain protein 2.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
CL C0021; CH+homeo.
XX
SZ 3005 AA; 332.0 kDa (cDNA) (calc.).
XX
SQ MSSFDVETFNGKIVYNLDGSAHIIATDNTNGGGSGSGQNCYGSTTNSLKNLSKDKGRGQE
SQ EKDIEHPSQYHREQSDNKRQEEAVDNRPGVESLGSACYKSSPKIHSFRVVSAQDANSTCQ
SQ DQIRAFKIQKPILMCFICKLSFGNVKSFSLHANTEHRLNLEELDQQLLNREYSSAIIQRN
SQ MDEKPQISFLQPLANNDASADTNDTEKLQTATEGSDATLPSSPQPVFRNDSELEPENKQE
SQ TEQNRLLNQDREQEPESDQHTSSSKMAAPSAYIPLSSPKVAGKLTVKFGSLNSATAKTNN
SQ LSKVSSTSSPPSTYASGEVLSPSTDNISNHKSTHCNQETEPPSSSSSEVEMKIGSMSTSP
SQ QTNDSDVPCSGFLQMQHMTTGGAYTPQVSSFHASLAALAAHESNDNRVKLITEFLQQQLQ
SQ QHQSSLFPSPCPDHPDLNGVDCKTCELLDIQQRSKSPSSSHHQFSQSLPQLQIQSQPQQT
SQ PHRSPCSNSVALPVSPSASSVASVGNASTATSSFTIGACSEHINGRPQGVDCARCEMLLN
SQ SARLNSGVQMSTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGQQHPR
SQ LARGESYSCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQELNSSQNMVAAAAAAAV
SQ TGKLLLSSSSPQVTAACPSNSGSGAGSGSSNIVGGTASLSGNATPSVTGANSSNANAGSN
SQ TNNAGTKPKPSFRCDICSYDTSVARNLRIHMTSEKHTHNMAVLQNNIKHIQAFNFLQQQQ
SQ QSGTGNIASHSSGSFMPEVALADLAYNQALMIQLLHQQQQHQQSANTKLSPSSSPVSTPD
SQ QFSFSPKPIKLNHGTGAAMGIGMAMGMGMSHSNEVSCELSGDPHPLTKTDKWPMAFYSCL
SQ VCDCYSTNNLDDLNQHLLLDRSRQSSSASSEIMVIHNNNYICRLCNYKTNLKANFQLHSK
SQ TDKHLQKLNFINHIREGGPQNEYKMQYQQQQLAANVVQLKCNCCDFHTNSIQKLSLHTQQ
SQ MRHDTMRMIFQHLLYIVQQSEMHNKSSGSAEDDPQCACPDEDQQLQLQSSKKLLLCQLCN
SQ FTAQNIHEMVQHVKGIRHLQVEQFICLQRRSENQEIPALNEVFKVTEWVMENEDVSLAPG
SQ LNLARTTTNDATTDASYAAASSAAVPAIPDVSMFSPTSPSSCATSCDKNLSQIVLPNVNN
SQ LGSGVPTTVFKCNLCEYFVQSKSEIAAHIETEHSCAESDEFITIPTNTAALQAFQTAVAA
SQ AALAAVHQRCAVINPPTQDTVDEDKDLDTNVSDGPVGIKQERLEQEVDRTTSMDVTKDLA
SQ SQATDFGAPESPKVAETEVGVQCPLCLENHFREKQYLEDHLTSVHSVTRDGLSRLLLLVD
SQ QKALKKESTDIACPTDKAPYANTNALERAPTPIENTCNVSLIKSTSANPSQSVSLQGLSC
SQ QQCEASFKHEEQLLKHAQQNQHFSLQNGEYLCLAASHISRPCFMTFRTIPTMISHFQDLH
SQ MSLIISERHVYKYRCKQCSLAFKTQEKLTTHMLYHSMRDATKCSFCQRNFRSTQALQKHM
SQ EQAHAEDGTPSTRTNSPQTPMLSTEETHKHLLAESHAVEREVSGSDVSPIELETHLNKET
SQ RHLSPTPMSLDSQSHQKHLATFAALLKQQQCNSDAGGLHPEALSMSTGEMPPQLQGLQNL
SQ QHIQQHFGAVAAAAGLPINPVDMLNIMQFHHLMSLNFMNLAPPLVFGANAAGNAVSGPSA
SQ LNNSITTSTATSASGLGDTHLTSGVSSIPVDSGKATAVPPQTQLNANANSQQLASNQKRA
SQ RTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSP
SQ YNFNNPPSTTLNLEEYERTGQAKVTPLNDTCSVAVTGPMTSSTISLPPSGNINLSSKENA
SQ TSKVLAAGKANASGPVTFSATVPVSTPLSRPESTNSSGNISDYIGNNIFFGQLGSKEQIL
SQ PYSLDGQIKSEPQDDMIGATDFAYQTKQHSSFSFLKQQQDLVDPPEQCLTNQNADTAQDQ
SQ SLLAGSSLASNCQSQQQINIFETKSESGSSDVLSRPPSPNSGAAGNVYGSMNDLLNQQLE
SQ NMGSNMGPPKKMQIVGKTFEKNVAPMVTSGSVSTQFESNSSNSSSSSSSTSGGKRANRTR
SQ FTDYQIKVLQEFFENNSYPKDSDLEYLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNNT
SQ LFENEETKKQNINYACKKCNLVFQRYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAQNL
SQ SSEDSNSSMDIHHVGICPPGSAVASHTLSTPGSAAPLPGQYTQHSFGALPSPQHLFAKSS
SQ SLTDFSPSTTPTPPQRERSNSLDQIQRPPKFDCDKCELNFNQLEKLREHQLLHLMNPGNI
SQ CSDVGQNSNPEANFGPFGSILQSLQQAAAQQQQQHHQQPPTKKRKYSDCSSNADEMQSLS
SQ ELEASQKKHEYLYKYFMQNETSQEVKQQFLMQQQQKKLEQGNECDFELDFLTNFYQQNEL
SQ KKVSNYDFLLQYYRTHEEAKSSQQHTFSSSKKPTIEFLLQYYQLNESKKFFQLVASPQII
SQ PDVPGYKPSLRIPKSTSDEAPYIGETSLEQATELQREKQDEQLRIDRPSEENDLSMNKNK
SQ VENINNNNINVDQSNLTETNGGVPSVETKEECTQESSLIAMDDENKYLCTRSKQKDDKEK
SQ SHYLHNLEDFLDATMIENNSQTLTFNDDEKACQKDELTQNSNAIEKRSSVSPVNVSSKQN
SQ KRLRTTILPEQLNFLYECYQSESNPSRKMLEEISKKVNLKKRVVQVWFQNSRAKDKKSRN
SQ QRHYAHISDDNSYDGSSGKEVYSDLRSNGITVDTDLETNLQDCQLCQVTQVNIRKHAFSV
SQ EHISKMKKLLEQTTELYAQSNGSGSEDNDSDREKRFYNLSKAFLLQHVVTNATSHAIHTA
SQ RQDSDVIAEGNCILNYDTNGGDSKSHVQHNLPNEVVSEDARKIAGNQELMQQLFNRNHIT
SQ VIGGK
XX
SC Swiss-Prot#P28167
XX
FT 124 787 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 133 156 
SM00355; c2h2final6.
FT 559 582 
PF00096; zf-C2H2.
FT 559 582 
SM00355; c2h2final6.
FT 559 587 
PS50157; ZINC_FINGER_C2H2_2.
FT 614 638 
PF00096; zf-C2H2.
FT 614 638 
SM00355; c2h2final6.
FT 614 643 
PS50157; ZINC_FINGER_C2H2_2.
FT 732 756 
PF00096; zf-C2H2.
FT 732 756 
SM00355; c2h2final6.
FT 897 918 SM00355; c2h2final6.
FT 940 964 SM00355; c2h2final6.
FT 999 1023 SM00355; c2h2final6.
FT 1074 1098 SM00355; c2h2final6.
FT 1210 1233 SM00355; c2h2final6.
FT 1341 1365 SM00355; c2h2final6.
FT 1438 1462 SM00355; c2h2final6.
FT 1438 1467 PS50157; ZINC_FINGER_C2H2_2.
FT 1513 1535 PF00096; zf-C2H2.
FT 1513 1535 SM00355; c2h2final6.
FT 1513 1540 PS50157; ZINC_FINGER_C2H2_2.
FT 1541 1564 PF00096; zf-C2H2.
FT 1541 1564 SM00355; c2h2final6.
FT 1541 1569 PS50157; ZINC_FINGER_C2H2_2.
FT 1795 1855 PS50071; HOMEOBOX_2.
FT 1797 1859 SM00389; HOX_1.
FT 1798 1854 PF00046; Homeobox domain.
FT 2152 2212 PS50071; HOMEOBOX_2.
FT 2154 2216 SM00389; HOX_1.
FT 2155 2211 PF00046; Homeobox domain.
FT 2234 2256 PF00096; zf-C2H2.
FT 2234 2256 SM00355; c2h2final6.
FT 2234 2261 PS50157; ZINC_FINGER_C2H2_2.
FT 2371 2393 PF00096; zf-C2H2.
FT 2371 2393 PS50157; ZINC_FINGER_C2H2_2.
FT 2371 2393 SM00355; c2h2final6.
FT 2758 2818 PS50071; HOMEOBOX_2.
FT 2760 2822 SM00389; HOX_1.
FT 2761 2817 PF00046; Homeobox domain.
XX
SF 16 scattered zinc fingers and 3 homeo domains;
XX
CP CNS of late embryos.
XX
BS R09578.
BS R02507.
XX
DR TRANSPATH: MO000025271.
DR EMBL: M63450;
DR UniProtKB: P28167;
DR FLYBASE: FBgn0004607; zfh2.
XX
RN [1]; RE0001192.
RX PUBMED: 1680376.
RA Fortini M. E., Lai Z., Rubin G. M.
RT The Drosophila zfh-1 and zfh-2 genes encode novel proteins containing both zinc-finger and homeodomain motifs
RL Mech. Dev. 34:113-122 (1991).
RN [2]; RE0001193.
RX PUBMED: 1680377.
RA Lai Z., Fortini M. E., Rubin G. M.
RT The embryonic expression patterns of zfh-1 and zfh-2, two Drosophila genes encoding novel zinc-finger and homeodomain proteins
RL Mech. Dev. 34:123-134 (1991).
RN [3]; RE0015328.
RX PUBMED: 7902124.
RA Kalionis B., O'Farrell P. H.
RT A universal target sequence is bound in vitro by diverse homeodomains
RL Mech. Dev. 43:57-70 (1993).
XX
//