AC T01276
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ID T01276
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DT 19.10.1994 (created); ewi.
DT 11.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Sox-4
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SY EVI16; Sox-4; SOX4; SRY (sex determining region Y)-box 4.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002877 SOX4; HGNC: SOX4.
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CL C0015; HMG; 4.1.1.3.1.
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IN T00671 p53; human, Homo sapiens.
IN T18226 plakoglobin; human, Homo sapiens.
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MX M01308 V$SOX4_01.
MX M07614 V$SOX4_Q3.
MX M03849 V$SOX4_Q5.
MX M07268 V$SOX4_Q5_02.
MX M02909 V$SOX5_07.
MX M08899 V$SOX_Q4.
MX M01014 V$SOX_Q6.
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BS R63081.
BS R63803.
BS R63804.
BS R33555.
BS R63788.
BS R63789.
BS R63790.
BS R63793.
BS R63795.
BS R63796.
BS R63811.
BS R63812.
BS R63491.
BS R63813.
BS R63814.
BS R63489.
BS R63490.
BS R63484.
BS R63485.
BS R63486.
BS R63487.
BS R63482.
BS R63799.
BS R63800.
BS R63801.
BS R63802.
BS R63797.
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DR TRANSPATH: MO000025546.
DR UniProtKB: Q06945;
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RN [1]; RE0004341.
RX PUBMED: 1614875.
RA Denny P., Swift S., Brand N., Dabhade N., Barton P., Ashworth A.
RT A conserved family of genes related to the testis determining gene, SRY
RL Nucleic Acids Res. 20:2887-2887 (1992).
RN [2]; RE0005012.
RX PUBMED: 8268656.
RA Farr C. J., Easty D. J., Ragoussis J., Collignon J., Lovell-Badge R., Goodfellow P. N.
RT Characterization and mapping of the human SOX4 gene
RL Mamm. Genome 4:577-584 (1993).
RN [3]; RE0017072.
RX PUBMED: 9730625.
RA Critcher R., Stitson R. N., Wade-Martins R., Easty D. J., Farr C. J.
RT Assignment of Sox4 to mouse chromosome 13 bands A3-A5 by fluorescence in situ hybridization; refinement2 of the human SOX4 location to 6p22.3 and of SOX20 to chromosome 17p12.3
RL Cytogenet. Cell Genet. 81:294-295 (1998).
RN [4]; RE0067035.
RX PUBMED: 19234109.
RA Pan X., Zhao J., Zhang W. N., Li H. Y., Mu R., Zhou T., Zhang H. Y., Gong W. L., Yu M., Man J. H., Zhang P. J., Li A. L., Zhang X. M.
RT Induction of SOX4 by DNA damage is critical for p53 stabilization and function.
RL Proc. Natl. Acad. Sci. USA 106:3788-3793 (2009).
RN [5]; RE0067089.
RX PUBMED: 12216117.
RA Ahn S. G., Kim H. S., Jeong S. W., Kim B. E., Rhim H., Shim J. Y., Kim J. W., Lee J. H., Kim I. K.
RT Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A(2) and delta(12)-PGJ(2).
RL Exp. Mol. Med. 34:243-249 (2002).
RN [6]; RE0067112.
RX PUBMED: 17875931.
RA Sinner D., Kordich J. J., Spence J. R., Opoka R., Rankin S., Lin S. C., Jonatan D., Zorn A. M., Wells J. M.
RT Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells.
RL Mol. Cell. Biol. 27:7802-7815 (2007).
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