AC T06215
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ID T06215
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DT 28.09.2004 (created); ewi.
DT 18.11.2004 (updated); oke.
CO Copyright (C), QIAGEN.
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FA ER-beta2
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SY estrogen receptor beta2; NR3A2.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G010022 Esr2.
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CL C0002; CC (rec).
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SZ 548 AA; 61.2 kDa (calc.).
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SQ MEIKNSPSSLSSPASYNCSQSILPLEHGPIYIPSSYVDNRHEYSAMTFYSPAVMNYSVPG
SQ STSNLDGGPVRLSTSPNVLWPTSGHLSPLATHCQSSLLYAEPQKSPWCEARSLEHTLPVN
SQ RETLKRKLSGSSCASPVTSPNAKRDAHFCPVCSDYASGYHYGVWSCEGCKAFFKRSIQGH
SQ NDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRERCGYRIVRRQRSSSEQVH
SQ CLSKAKRNGGHAPRVKELLLSTLSPEQLVLTLLEAEPPNVLVSRPSMPFTEASMMMSLTK
SQ LADKELVHMIGWAKKIPGFVELSLLDQVRLLESCWMEVLMVGLMWRSIDHPGKLIFAPDL
SQ VLDRSSEDPHWHVAQMKSAAPRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKA
SQ MILLNSSMYPLASANQEAESSRKLTHLLNAVTDALVWVIAKSGISSQQQSVRLANLLMLL
SQ SHVRHISNKGMEHLLSMKCKNVVPVYDLLLEMLNAHTLRGYKSSISGSECSSTEDSKNKE
SQ SSQNLQSQ
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SC translated from EMBL #AJ002603 and edited
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FT 146 217 SM00399; c4gold.
FT 146 221 PS51030; NUCLEAR_REC_DBD_2.
FT 147 222 PF00105; Zinc finger, C4 type (two domains).
FT 176 429 PF00478; IMP dehydrogenase / GMP reductase domai.
FT 300 487 SM00430; holi.
FT 303 512 PF00104; Ligand-binding domain of nuclear hormon.
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SF most ER-beta(rat) sequences in nucleotide database start with M46;
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MX M00959 V$ER_Q6_02.
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DR TRANSPATH: MO000043816.
DR EMBL: AB012721;
DR EMBL: AF042059;
DR EMBL: AJ002602;
DR EMBL: AJ002603;
DR UniProtKB: Q62986-2;
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RN [1]; RE0016546.
RX PUBMED: 9600083.
RA Maruyama K., Endoh H., Sasaki-Iwaoka H., Kanou H., Shimaya E., Hashimoto S., Kato S., Kawashima H.
RT A novel isoform of rat estrogen receptor beta with 18 amino acid insertion in the ligand binding domain as a putative dominant negative regular of estrogen action
RL Biochem. Biophys. Res. Commun. 246:142-147 (1998).
RN [2]; RE0024838.
RX PUBMED: 9492041.
RA Petersen D. N., Tkalcevic G. T., Koza-Taylor P. H., Turi T. G., Brown T. A.
RT Identification of estrogen receptor beta2, a functional variant of estrogen receptor beta expressed in normal rat tissues.
RL Endocrinology 139:1082-1092 (1998).
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