AC T09208
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ID T09208
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DT 09.08.2006 (created); res.
DT 16.08.2006 (updated); res.
CO Copyright (C), QIAGEN.
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FA CA150-isoform1
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SY TAF2S; TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kDa; TATA box-binding protein-associated factor 2S; TCERG1; transcription elongation regulator 1 (CA150).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009474 TCERG1; HGNC: TCERG1.
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SZ 1098 AA; 124.0 kDa (calc.).
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SQ MAERGGDGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPP
SQ PPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMP
SQ PVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQ
SQ AQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ
SQ AQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPT
SQ TQDQTPSSAVSVATPTVSVSTPARTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPP
SQ VMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIA
SQ ASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEP
SQ SEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTG
SQ DERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKW
SQ QFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLE
SQ ARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERRE
SQ KKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAA
SQ RKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLF
SQ KQYIEKIAKNLDSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAI
SQ QNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREH
SQ FRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFR
SQ TLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDR
SQ RGPPPPPTASEPTRRSTK
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SC translated from EMBL #AF017789
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FT 131 164 PS50020; WW_DOMAIN_2.
FT 132 164 SM00456; ww_5.
FT 133 162 PF00397; WW domain.
FT 146 522 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 429 462 PS50020; WW_DOMAIN_2.
FT 430 462 SM00456; ww_5.
FT 431 460 PF00397; WW domain.
FT 529 561 SM00456; ww_5.
FT 530 559 PF00397; WW domain.
FT 532 561 PS50020; WW_DOMAIN_2.
FT 659 712 SM00441; FF.
FT 661 709 PF01846; FF domain.
FT 725 779 SM00441; FF.
FT 727 776 PF01846; FF domain.
FT 792 846 SM00441; FF.
FT 794 843 PF01846; FF domain.
FT 896 952 SM00441; FF.
FT 898 949 PF01846; FF domain.
FT 954 1010 SM00441; FF.
FT 956 1007 PF01846; FF domain.
FT 1012 1077 SM00441; FF.
FT 1014 1074 PF01846; FF domain.
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IN T18011 ESET; human, Homo sapiens.
IN T18835 Mi2-alpha; human, Homo sapiens.
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DR TRANSPATH: MO000084615.
DR EMBL: AF017789;
DR UniProtKB: O14776;
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RN [1]; RE0048055.
RX PUBMED: 15383276.
RA Goehler H., Lalowski M., Stelzl U., Waelter S., Stroedicke M., Worm U., Droege A., Lindenberg K. S., Knoblich M., Haenig C., Herbst M., Suopanki J., Scherzinger E., Abraham C., Bauer B., Hasenbank R., Fritzsche A., Ludewig A. H., Bussow K., Coleman S. H., Gutekunst C. A., Landwehrmeyer B. G., Lehrach H., Wanker E. E.
RT A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease.
RL Mol. Cell 15:853-865 (2004).
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