AC T09225
XX
ID T09225
XX
DT 16.08.2006 (created); din.
DT 24.04.2008 (updated); grs.
CO Copyright (C), QIAGEN.
XX
FA En-1
XX
SY Engrailed 1; Gg-en.1 (chick); Hu-en.1 (human); Mo-en.1.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G006023 En1.
XX
CL C0006; homeo.
XX
SZ 401 AA; 40.9 kDa (cDNA) (calc.).
XX
SQ MEEQQPEPKSQRDSGLGAVAAAAPSGLSLSLSPGASGSSGSDGDSVPVSPQPAPPSPPAA
SQ PCLPPLAHHPHLPPHPPPPPPPPPPPPQHLAAPAHQPQPAAQLHRTTNFFIDNILRPDFG
SQ CKKEQPLPQLLVASAAAGGGAAAGGGSRVERDRGQTGAGRDPVHSLGTRASGAASLLCAP
SQ DANCGPPDGSQPATAVGAGASKAGNPAAAAAAAAAAAAAAVAAAAAAASKPSDSGGGSGG
SQ NAGSPGAQGAKFPEHNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRT
SQ RKLKKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWF
SQ QNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKDESE
XX
SC Swiss-Prot#P09065
XX
FT 25 362 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 310 370 
PS50071; HOMEOBOX_2.
FT 312 374 
SM00389; HOX_1.
FT 313 369 
PF00046; Homeobox domain.
XX
IN T09446 c-Jun; Mammalia.
XX
MX M00396 V$EN1_01.
MX M01365 V$EN1_02.
XX
BS R09094.
BS R09095.
BS R09096.
BS R09097.
BS R09098.
BS R09099.
BS R09100.
BS R09101.
BS R09102.
BS R09103.
XX
DR TRANSPATH: MO000085063.
DR EMBL: L12702;
DR EMBL: L12703;
DR UniProtKB: P09065;
XX
RN [1]; RE0003871.
RX PUBMED: 8096059.
RA Catron K. M., Iller N., Abate C.
RT Nucleotides flanking a conserved TAAT core dictate the DNA binding specifity of three murine homeodomain proteins
RL Mol. Cell. Biol. 13:2354-2365 (1993).
RN [2]; RE0005044.
RX PUBMED: 2892757.
RA Joyner A. L., Martin G. R.
RT En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis
RL Genes Dev. 1:29-38 (1987).
RN [3]; RE0005045.
RX PUBMED: 1363401.
RA Logan C., Hanks M. C., Noble-Topham S., Nallainathan D., Provart N. J., Joyner A. L.
RT Cloning and sequence comparison of the mouse, human, and chicken engrailed genes reveal potential functional domains and regulatory regions
RL Dev. Genet. 13:345-358 (1992).
RN [4]; RE0005046.
RX PUBMED: 2416459.
RA Joyner L. A., Kornberg T., Coleman K. G., Cox D. R., Martin G. R.
RT Expression during embryogenesis of a mouse gene with sequence homology to the Drosophila engrailed gene
RL Cell 43:29-37 (1985).
RN [5]; RE0005047.
RX PUBMED: 1980115.
RA Holland P. W. H., Williams N. A.
RT Conservation of engrailed-like homeobox sequences during vertebrate evolution
RL FEBS Lett. 277:250-252 (1990).
RN [6]; RE0005048.
RX PUBMED: 7624797.
RA Hanks M., Wurst W., Anson-Cartwright L., Auerbach A. B., Joyner A. L.
RT Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2
RL Science 269:679-682 (1995).
RN [7]; RE0005050.
RX PUBMED: 1534034.
RA McMahon A. P., Joyner A. L., Bradley A., McMahon J. A.
RT The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum
RL Cell 69:581-595 (1992).
RN [8]; RE0005498.
RX PUBMED: 7925010.
RA Wurst W., Auerbach A. B., Joyner A. L.
RT Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum
RL Development 120:2065-2075 (1994).
RN [9]; RE0015359.
RA Frohman M. A., Dickinson M. E., Hogan B. L. M., Martin G. R.
RT Mapping of Gbx-1 to mouse chromosome 5 and Gbx-2 to mouse chromosome 1
RL Mouse Genome 91:323-325 (1993).
RN [10]; RE0052694.
RX PUBMED: 11551904.
RA Schaefer L. K., Wang S., Schaefer T. S.
RT Functional interaction of Jun and homeodomain proteins.
RL J. Biol. Chem. 276:43074-43082 (2001).
XX
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