AC T09226
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ID T09226
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DT 16.08.2006 (created); din.
DT 08.11.2012 (updated); uat.
CO Copyright (C), QIAGEN.
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FA Lhx2
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SY ap; Apterous; LH-2; LH2A; LHX2; LIM homeobox protein 2; Lim2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004532 Lhx2.
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CL C0025; LIM-homeo.
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SZ 406 AA; 44.4 kDa (cDNA) (calc.).
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SQ MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKI
SQ SDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHL
SQ GISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAH
SQ FNHADVAAAAAAAAAAKSAGLGSAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAY
SQ NAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLA
SQ QKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKTSDATLQTGTPSGPASELSNASLSP
SQ SSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
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SC translated from EMBL #AF124734
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FT 1 321 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 51 112 PS50023; LIM_DOMAIN_2.
FT 52 105 SM00132; lim_4.
FT 53 111 PF00412; LIM domain.
FT 113 175 PS50023; LIM_DOMAIN_2.
FT 114 168 SM00132; lim_4.
FT 115 174 PF00412; LIM domain.
FT 264 324 PS50071; HOMEOBOX_2.
FT 266 328 SM00389; HOX_1.
FT 267 323 PF00046; Homeobox domain.
FT 267 323 PS50558; LIM_HOMEODOMAIN.
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IN T00682 Pax-6; zebra fish, Brachydanio rerio.
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MX M01325 V$LHX2_01.
MX M07047 V$LHX2_Q4.
MX M07385 V$LHX2_Q6.
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BS R09043.
BS R40682.
BS R22327.
BS R22328.
BS R22318.
BS R22319.
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DR TRANSPATH: MO000085065.
DR EMBL: AF124734;
DR UniProtKB: Q9Z0S2;
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RN [1]; RE0004773.
RX PUBMED: 7678338.
RA Xu Y., Baldassare M., Fisher P., Rathbun G., Oltz E. M., Yancopoulos G. D., Jessell T. M., Alt F. W.
RT LH-2: a LIM/homeodomain gene expressed in developing lymphocytes and neural cells
RL Proc. Natl. Acad. Sci. USA 90:227-231 (1993).
RN [2]; RE0015588.
RX PUBMED: 8817562.
RA Matsumoto K., Tanaka T., Furuyama T., Kashihara Y., Ishii N., Tohyama M., Kitanaka J., Takemura M., Mori T., Wanaka A.
RT Differential expression of LIM-homeodomain genes in the embryonic murine brain
RL Neurosci. Lett. 211:147-150 (1996).
RN [3]; RE0017735.
RX PUBMED: 10051612.
RA Rincon-Limas D. E., Lu C. H., Canal I., Calleja M., Rodriguez-Esteban C., Izpisua-Belmonte J. C., Botas J.
RT Conservation of the expression and function of apterous orthologs in Drosophila and mammals.
RL Proc. Natl. Acad. Sci. USA 96:2165-2170 (1999).
RN [4]; RE0047970.
RX PUBMED: 11069920.
RA Mikkola I., Bruun J. A., Holm T., Johansen T.
RT Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins.
RL J. Biol. Chem. 276:4109-4118 (2001).
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