AC T10109
XX
ID T10109
XX
DT 10.01.2007 (created); kau.
DT 07.02.2014 (updated); hna.
CO Copyright (C), QIAGEN.
XX
FA INSAF
XX
SY IEF-1; insulin activator factor.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
CL C0010; bHLH.
XX
SZ 744 AA; 84.0 kDa (cDNA) (calc.).
XX
SQ MNTKKLAVTNGVVGLVGGIALLLGGWIVLYSGNRWNRTFAIVNVLFLLLKIATLVLGIVG
SQ LVQFSKEAVITKAPSVLLVVGGALAIIPFMGWIGGILSIIGGSIYLAISRNLSNKMAFIA
SQ VHIKKGDHDMINNSYLLKADLKREKDIPLISRESIIKLAKAHERGDVRYLNEAETNVYDL
SQ LTKIEVKRLASLYKSFIFDFSIEDSTVSYTFADIEEAIRDNIGVKNKRLLEDSTNLMSDI
SQ IRFAVTPVDYIFDFHKNDNGNLEVQRDQVLERFIEVLEQQTYENVWSDLMKYPFDNQTHG
SQ IRKHLMLGVAASTGKSIILEAIGKLYEASASFKSNRPENGFDAANWNADIIDKFVVLLDD
SQ DNPNVSINEDYLKNFLSNNMPQQLARGGGQRWSEIYYGSSVIALNTAPDFLKNQQNNKRV
SQ IFLKLTQSIEEMFTSEELNHLHNLEPKHILGYVNSEPTKLFKWRNDWSGVIEDLKEDVKQ
SQ HISMRGYASLNDLKKTFGDKVMRDYQRTVEKAKNITVNGEAFYGLRQDAIIDEPYRVDQL
SQ TFSAFINLHDVIGERNFESLDEFKNDIEEYGKLKKEEQPLFSPAVYHDELTKANLTGFVG
SQ VVLDIDGANAADMDELEDKIAMTGISAVAWETASSTPSSLRARIWFYRVGGGLEEYASLV
SQ KKIAMKIDEPFDRASMPAEHRFFIGGTNVRLINTDSTAAENKPMTDMKKRGLVRAVQNAK
SQ DGEREQITYWALMRAEQENGGKEF
XX
SC conceptually translated from EMBL/GenBank/DDBJ #S73205
XX
FT 207 518 PF00478; IMP dehydrogenase / GMP reductase domain.
XX
IN T17415 E12; Mammalia.
XX
BS R60166.
XX
DR TRANSPATH: MO000095972.
DR EMBL: S73205;
DR UniProtKB: Q16219;
XX
RN [1]; RE0001479.
RX PUBMED: 1996108.
RA Leshkowitz D., Walker M. D.
RT Extinction of insulin gene expression in hybrids between beta cells and fibroblasts is accompanied by loss of the putative beta-cell-specific transcription factor IEF1
RL Mol. Cell. Biol. 11:1547-1552 (1991).
RN [2]; RE0004052.
RX PUBMED: 7935390.
RA Robinson G. L. W., Cordle S. R., Henderson E., Weil P. A., Teitelman G., Stein R.
RT Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression
RL Mol. Cell. Biol. 14:6704-6714 (1994).
XX
//