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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T10109 XX ID T10109 XX DT 10.01.2007 (created); kau. DT 07.02.2014 (updated); hna. CO Copyright (C), QIAGEN. XX FA INSAF XX SY IEF-1; insulin activator factor. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX CL C0010; bHLH. XX SZ 744 AA; 84.0 kDa (cDNA) (calc.). XX SQ MNTKKLAVTNGVVGLVGGIALLLGGWIVLYSGNRWNRTFAIVNVLFLLLKIATLVLGIVG SQ LVQFSKEAVITKAPSVLLVVGGALAIIPFMGWIGGILSIIGGSIYLAISRNLSNKMAFIA SQ VHIKKGDHDMINNSYLLKADLKREKDIPLISRESIIKLAKAHERGDVRYLNEAETNVYDL SQ LTKIEVKRLASLYKSFIFDFSIEDSTVSYTFADIEEAIRDNIGVKNKRLLEDSTNLMSDI SQ IRFAVTPVDYIFDFHKNDNGNLEVQRDQVLERFIEVLEQQTYENVWSDLMKYPFDNQTHG SQ IRKHLMLGVAASTGKSIILEAIGKLYEASASFKSNRPENGFDAANWNADIIDKFVVLLDD SQ DNPNVSINEDYLKNFLSNNMPQQLARGGGQRWSEIYYGSSVIALNTAPDFLKNQQNNKRV SQ IFLKLTQSIEEMFTSEELNHLHNLEPKHILGYVNSEPTKLFKWRNDWSGVIEDLKEDVKQ SQ HISMRGYASLNDLKKTFGDKVMRDYQRTVEKAKNITVNGEAFYGLRQDAIIDEPYRVDQL SQ TFSAFINLHDVIGERNFESLDEFKNDIEEYGKLKKEEQPLFSPAVYHDELTKANLTGFVG SQ VVLDIDGANAADMDELEDKIAMTGISAVAWETASSTPSSLRARIWFYRVGGGLEEYASLV SQ KKIAMKIDEPFDRASMPAEHRFFIGGTNVRLINTDSTAAENKPMTDMKKRGLVRAVQNAK SQ DGEREQITYWALMRAEQENGGKEF XX SC conceptually translated from EMBL/GenBank/DDBJ #S73205 XX FT 207 518 PF00478; IMP dehydrogenase / GMP reductase domain. XX IN T17415 E12; Mammalia. XX BS R60166. XX DR TRANSPATH: MO000095972. DR EMBL: S73205; DR UniProtKB: Q16219; XX RN [1]; RE0001479. RX PUBMED: 1996108. RA Leshkowitz D., Walker M. D. RT Extinction of insulin gene expression in hybrids between beta cells and fibroblasts is accompanied by loss of the putative beta-cell-specific transcription factor IEF1 RL Mol. Cell. Biol. 11:1547-1552 (1991). RN [2]; RE0004052. RX PUBMED: 7935390. RA Robinson G. L. W., Cordle S. R., Henderson E., Weil P. A., Teitelman G., Stein R. RT Isolation and characterization of a novel transcription factor that binds to and activates insulin control element-mediated expression RL Mol. Cell. Biol. 14:6704-6714 (1994). XX //