AC T10770
XX
ID T10770
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DT 28.08.2007 (created); kma.
DT 03.12.2009 (updated); jul.
CO Copyright (C), QIAGEN.
XX
FA Pbx2
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SY pre B-cell leukemia transcription factor 2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002137 PBX2; HGNC: PBX2.
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CL C0006; homeo.
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SZ 430 AA; 45.9 kDa (cDNA) (calc.).
XX
SQ MDERLLGPPPPGGGRGGLGLVSGEPGGPGEPPGGGDPGGGSGGVPGGRGKQDIGDILQQI
SQ MTITDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRSSQEEEPVDPQLMRLDN
SQ MLLAEGVAGPEKGGGSAAAAAAAAASGGGVSPDNSIEHSDYRSKLAQIRHIYHSELEKYE
SQ QACNEFTTHVMNLLREQSRTRPVAPKEMERMVSIIHRKFSAIQMQLKQSTCEAVMILRSR
SQ FLDARRKRRNFSKQATEVLNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRI
SQ RYKKNIGKFQEEANIYAVKTAVSVTQGGHSRTSSPTPPSSAGSGGSFNLSGSGDMFLGMP
SQ GLNGDSYSASQVESLRHSMGPGGYGDNLGGGQMYSPREMRANGSWQEAVTPSSVTSPTEG
SQ PGSVHSDTSN
XX
SC translated from EMBL #X59842
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FT 41 243 
PF03792; PBX domain.
FT 242 305 
PS50071; HOMEOBOX_2.
FT 244 309 
SM00389; HOX_1.
FT 245 304 
PF00046; Homeobox domain.
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IN T14354 hoxa9; mouse, Mus musculus.
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MX M00998 V$PBX_Q3.
MX M07304 V$PBX_Q5.
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BS R15380.
BS R08497.
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DR TRANSPATH: MO000112883.
DR EMBL: U89336;
DR EMBL: X59842;
DR EMBL: X80700;
DR UniProtKB: P40425;
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RN [1]; RE0005181.
RX PUBMED: 1682799.
RA Monica K., Saltman D., Nourse J., Galili N., Cleary M. L.
RT PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1
RL Mol. Cell. Biol. 11:6149-6157 (1991).
RN [2]; RE0014544.
RX PUBMED: 9336443.
RA Burglin T. R.
RT Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals
RL Nucleic Acids Res. 25:4173-4180 (1997).
RN [3]; RE0015488.
RX PUBMED: 9482739.
RA Berthelsen J., Zappavigna V., Mavilio F., Blasi F.
RT Prep1, a novel functional partner of Pbx proteins
RL EMBO J. 17:1423-1433 (1998).
RN [4]; RE0024570.
RX PUBMED: 8183558.
RA LeBrun D. P., Cleary M. L.
RT Fusion with E2A alters the transcriptional properties of the homeodomain protein PBX1 in t(1;19) leukemias.
RL Oncogene 9:1641-1647 (1994).
RN [5]; RE0065074.
RX PUBMED: 10082572.
RA Shen W. F., Rozenfeld S., Kwong A., Kom ves L. G., Lawrence H. J., Largman C.
RT HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells.
RL Mol. Cell. Biol. 19:3051-3061 (1999).
XX
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