AC T13920
XX
ID T13920
XX
DT 10.01.2008 (created); djp.
DT 19.09.2014 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA EAR2
XX
SY COUP-TF3; ear-2; ERBAL2; NR2F6.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G009995 Nr2f6.
XX
CL C0002; CC (rec).
XX
SZ 390 AA; 42.0 kDa (cDNA) (calc.).
XX
SQ MAMVTGGWGDPGGDTNGVDKAGGSYPRATEDDSASPPGATSDAEPGDEERPGLQVDCVVC
SQ GDKSSGKHYGVFTCEGCKSFFKRTIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKKCFRV
SQ GMRKEAVQRGRIPHALPGPAACSPPGATGVEPFTGPPVSELIAQLLRAEPYPAAGRFGGG
SQ GAVLGIDNVCELAARLLFSTVEWARHAPFFPELPAADQVALLRLSWSELFVLNAAQAALP
SQ LHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVDKLGRLQVDAAEYGCLKAIALFTP
SQ DACGLSDPAHVESLQEKAQVALTEYVRAQYPSQPQRFGRLLLRLPALRAVPASLISKLFF
SQ MRLVGKTPIETLIRDMLLSGSTFNWPYGSG
XX
SC translated from EMBL #X76654
XX
FT 54 125 
SM00399; c4gold.
FT 54 129 
PS51030; NUCLEAR_REC_DBD_2.
FT 55 130 
PF00105; Zinc finger, C4 type (two domains).
FT 191 351 
SM00430; holi.
FT 194 376 
PF00104; Ligand-binding domain of nuclear hormon.
XX
IN T27831 BCL-11A; mouse, Mus musculus.
IN T09429 COUP-TF2; mouse, Mus musculus.
IN T10310 COUP-TF2; Mammalia.
IN T18922 ZFPM2; mouse, Mus musculus.
XX
MX M01728 V$EAR2_Q2.
MX M08805 V$EAR2_Q4.
XX
BS R36818.
XX
DR TRANSPATH: MO000120611.
DR EMBL: L25674; MMEAR2TFA.
DR EMBL: X76654; MMREAR2.
DR UniProtKB: P43136; EAR2_MOUSE.
XX
RN [1]; RE0024770.
RX PUBMED: 7947324.
RA Jonk L. J., de Jonge M. E., Pals C. E., Wissink S., Vervaart J. M., Schoorlemmer J., Kruijer W.
RT Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.
RL Mech. Dev. 47:81-97 (1994).
RN [2]; RE0024782.
RX PUBMED: 8194772.
RA Barnhart K. M., Mellon P. L.
RT The sequence of a murine cDNA encoding Ear-2, a nuclear orphan receptor.
RL Gene 142:313-314 (1994).
RN [3]; RE0051652.
RX PUBMED: 11382775.
RA Huggins G. S., Bacani C. J., Boltax J., Aikawa R., Leiden J. M.
RT Friend of GATA 2 physically interacts with chicken ovalbumin upstream promoter-TF2 (COUP-TF2) and COUP-TF3 and represses COUP-TF2-dependent activation of the atrial natriuretic factor promoter.
RL J. Biol. Chem. 276:28029-28036 (2001).
RN [4]; RE0051708.
RX PUBMED: 10318855.
RA Avram D., Ishmael J. E., Nevrivy D. J., Peterson V. J., Lee S. H., Dowell P., Leid M.
RT Heterodimeric interactions between chicken ovalbumin upstream promoter-transcription factor family members ARP1 and ear2.
RL J. Biol. Chem. 274:14331-14336 (1999).
RN [5]; RE0052267.
RX PUBMED: 10744719.
RA Avram D., Fields A., Pretty On Top K., Nevrivy D. J., Ishmael J. E., Leid M.
RT Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors.
RL J. Biol. Chem. 275:10315-10322 (2000).
XX
//