AC T14061
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ID T14061
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DT 19.02.2008 (created); jag.
DT 25.11.2011 (updated); grs.
CO Copyright (C), QIAGEN.
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FA HES-5
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SY hairy and enhancer of split 5 (Drosophila); Hes5.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014489 Hes5.
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CL C0010; bHLH.
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SZ 166 AA; 18.5 kDa (cDNA) (calc.).
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SQ MAPSTVAVEMLSPKEKNRLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPNSKLEKAD
SQ ILEMAVSYLKHSKAFAAAAGPKSLHQDYSEGYSWCLQEAVQFLTLHAASDTQMKLLYHFQ
SQ RPPAPAAPVKETPTPGAAPQPARSSTKAAASVSTSRQSACGLWRPW
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SC Swiss-Prot#Q03062
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FT 17 73 
PF00010; Helix-loop-helix DNA-binding domain.
FT 17 73 
PS50888; HLH.
FT 22 78 
SM00353; finulus.
FT 86 128 
PF07527; Hairy Orange.
FT 86 128 
SM00511; ORANGE.
FT 88 119 
PS51054; ORANGE.
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IN T23078 MASH-1; Mammalia.
IN T10436 Sox-10; Mammalia.
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BS R16655.
BS R16656.
BS R29843.
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DR TRANSPATH: MO000122782.
DR EMBL: D12516;
DR EMBL: D32132;
DR UniProtKB: Q03062;
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RN [1]; RE0003682.
RX PUBMED: 1400497.
RA Akazawa C., Sasai Y., Nakanishi S., Kageyama R.
RT Molecular characterization of a rat negative regulator with a basic helix-loop- helix structure predominantly expressed in the developing nervous system
RL J. Biol. Chem. 267:21879-21885 (1992).
RN [2]; RE0003795.
RX PUBMED: 7836401.
RA Takebayashi K., Akazawa C., Nakanishi S., Kageyama R.
RT Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5
RL J. Biol. Chem. 270:1342-1349 (1995).
RN [3]; RE0065082.
RX PUBMED: 17006542.
RA Liu A., Li J., Marin-Husstege M., Kageyama R., Fan Y., Gelinas C., Casaccia-Bonnefil P.
RT A molecular insight of Hes5-dependent inhibition of myelin gene expression: old partners and new players.
RL EMBO J. 25:4833-4842 (2006).
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