AC T00210
XX
ID T00210
XX
DT 27.10.1992 (created); ewi.
DT 29.11.2005 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA E74B
XX
SY E74B.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
GE G000097 Eip74EF.
XX
CL C0016; ETS.
XX
SZ 883 AA; 94.8 kDa (cDNA) (calc.).
XX
SQ MIMVQHLVAASAHNFASQAAASLVNVSSSSSSSSSSSSSSLSLSSSSSSSSLSSATPTPV
SQ ASPVTPTSPPPAAAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVN
SQ VEEPGAIVDTESVMARQSPSPVASTKVPESLEEISNKSPPVQEDEEESESVASDCREFKV
SQ LYNHLRQQQHHHSPSSPDKTRSTLDDVSKILWERKQQLQRSSVITAAPTLQPQQHQQPMS
SQ DIEDEETLEDVDDADADVEADAEDEELLEQYQNGYDSPLDLSLGGATSAAASAAAAASAV
SQ SRRRGRTYSGTESDDSAQCERARMRLKPERKAERSAAYKKSLMKRYYTEIPIVKQSTSPA
SQ PQQQLQQQHHLQQQQQQQPHNGSTFAGATALLHIKTEQNTLLTPLQLQQQQQQQQGLHGA
SQ AGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTATTGSFPPSPADSG
SQ VSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHTGTFLHPNLYQNN
SQ AANSLRNIWNRSVGVPDNYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFNAPTAATAAAS
SQ QRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQQQQ
SQ QHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLS
SQ ASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRR
SQ SREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNY
SQ ETMGRALRYYYQRGILAKVDGQRLVYHFVDVPKDIIEIDCNGV
XX
SC Swiss-Prot#P11536
XX
FT 465 817 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 624 633 
PF00904; Involucrin repeat.
FT 636 645 
PF00904; Involucrin repeat.
FT 786 871 
PF00178; Ets-domain.
FT 786 873 
SM00413; etsneu2.
FT 787 869 
PS50061; ETS_DOMAIN_3.
FT 789 859 
PS50140; HSF_ETS.
XX
FF ecdysone-induced;
FF expression pattern differs from that of E74A [2];
FF it peaks at 18-21 h during embryonal development, re-appearing at 96-120 h )late third instar larvae), increases again after 156 h (pupae) and reaches a maximum at 180-204 h, then declining sharply and being undetectable in adult flies [2] [3];
XX
DR TRANSPATH: MO000045949.
DR EMBL: M37083; DME74B.
DR EMBL: X15087; DM74E.
DR UniProtKB: P11536; E74B_DROME.
DR FLYBASE: FBgn0000567.
XX
RN [1]; RE0000194.
RX PUBMED: 2107982.
RA Burtis K. C., Thummel C. S., Jones C. W., Karim F. D., Hogness D. S.
RT The Drosophila 74EF early puff contains E74, a complex ecdysone-inducible gene that encodes two ets-related proteins
RL Cell 61:85-99 (1990).
RN [2]; RE0005365.
RX PUBMED: 1690603.
RA Thummel C. S., Burtis K. C., Hogness D. S.
RT Spatial and temporal patterns of E74 transcription during Drosophila development
RL Cell 61:101-111 (1990).
RN [3]; RE0005366.
RX PUBMED: 2501755.
RA Janknecht R., Taube W., Luedecke H. J., Pongs O.
RT Characterization of a putative transcription Factor gene expressed in the 20-OH-ecdysone inducible puff 74EF in Drosophila melanogaster
RL Nucleic Acids Res. 17:4455-4464 (1989).
XX
//