TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T00389 XX ID T00389 XX DT 26.01.1993 (created); hse. DT 22.07.2014 (updated); spk. CO Copyright (C), QIAGEN. XX FA NF-kappaB1 XX SY H2TF1; KBF1; NF-kappaB (p50); NF-kappaB1; NF-kappaB1 (p105); NFkappaB1 precursor (p105); NFkappaB1(p50); NFKB-p105; NFKB-p50; nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; p105; p50; p50/p105. XX OS rat, Rattus norvegicus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G014379 Nfkb1. XX CL C0020; Rel; XX SF constitutively expressed; SF synthesized as a precursor T01926; SF binds to DNA as homo- or heteromer T00587; SF 2 zinc finger motifs; XX CP rat liver, rat kidney [6]. XX FF implicated in MHC class II expression; XX IN T05016 RelA-p65; rat, Rattus norvegicus. XX MX M00194 V$NFKB_Q6. MX M00774 V$NFKB_Q6_01. MX M03557 V$P50_Q6. XX BS R20924. BS R20656. BS R02167. BS R01057. BS R34903. BS R21681. XX DR TRANSPATH: MO000019357. DR UniProtKB: Q63369; XX RN [1]; RE0000169. RX PUBMED: 2203533. RA Gilmore T. D. RT NF-kappaB, KBF1, dorsal, and related matters RL Cell 62:841-843 (1990). RN [2]; RE0000453. RX PUBMED: 2583102. RA Lenardo M., Rustgi A. K., Schievella A. R., Bernards R. RT Suppression of MHC class I gene expression by N-myc through enhancer inactivation RL EMBO J. 8:3351-3355 (1989). RN [3]; RE0001474. RX PUBMED: 2196446. RA Henseling U., Schmidt W., Schoeler H. R., Gruss P., Hatzopoulos A. K. RT A transcription factor interacting with the class I gene enhancer is inactive in tumorigenic cell lines which suppress major histocompatibility complex class I genes RL Mol. Cell. Biol. 10:4100-4109 (1990). RN [4]; RE0002491. RX PUBMED: 2247438. RA Rustgi A. K., van't Veer L., Bernards R. RT Two genes encode factors with NF-kappaB- and H2TF1-like DNA-binding properties RL Proc. Natl. Acad. Sci. USA 87:8707-8710 (1990). RN [5]; RE0054086. RX PUBMED: 8939960. RA Diaz-Guerra M. J., Velasco M., Martin-Sanz P., Bosca L. RT Evidence for common mechanisms in the transcriptional control of type II nitric oxide synthase in isolated hepatocytes. Requirement of NF-kappaB activation after stimulation with bacterial cell wall products and phorbol esters. RL J. Biol. Chem. 271:30114-30120 (1996). RN [6]; RE0052350. RX PUBMED: 11134901. RA Ramon O., Wong H. K., Joyeux M., Riondel J., Halimi S., Ravanat J. L., Favier A., Cadet J., Faure P. RT 2'-deoxyguanosine oxidation is associated with decrease in the DNA-binding activity of the transcription factor Sp1 in liver and kidney from diabetic and insulin-resistant rats. RL Free Radic. Biol. Med. 30:107-118 (2001). XX //