AC T00389
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ID T00389
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DT 26.01.1993 (created); hse.
DT 22.07.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA NF-kappaB1
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SY H2TF1; KBF1; NF-kappaB (p50); NF-kappaB1; NF-kappaB1 (p105); NFkappaB1 precursor (p105); NFkappaB1(p50); NFKB-p105; NFKB-p50; nuclear factor of kappa light chain gene enhancer in B-cells 1, p105; p105; p50; p50/p105.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014379 Nfkb1.
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CL C0020; Rel; 6.1.1.1.1.
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SF constitutively expressed;
SF synthesized as a precursor T01926;
SF binds to DNA as homo- or heteromer T00587;
SF 2 zinc finger motifs;
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CP rat liver, rat kidney [6].
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FF implicated in MHC class II expression;
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IN T05016 RelA-p65; rat, Rattus norvegicus.
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MX M00194 V$NFKB_Q6.
MX M00774 V$NFKB_Q6_01.
MX M03557 V$P50_Q6.
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BS R20924.
BS R20656.
BS R02167.
BS R01057.
BS R34903.
BS R21681.
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DR TRANSPATH: MO000019357.
DR UniProtKB: Q63369;
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RN [1]; RE0000169.
RX PUBMED: 2203533.
RA Gilmore T. D.
RT NF-kappaB, KBF1, dorsal, and related matters
RL Cell 62:841-843 (1990).
RN [2]; RE0000453.
RX PUBMED: 2583102.
RA Lenardo M., Rustgi A. K., Schievella A. R., Bernards R.
RT Suppression of MHC class I gene expression by N-myc through enhancer inactivation
RL EMBO J. 8:3351-3355 (1989).
RN [3]; RE0001474.
RX PUBMED: 2196446.
RA Henseling U., Schmidt W., Schoeler H. R., Gruss P., Hatzopoulos A. K.
RT A transcription factor interacting with the class I gene enhancer is inactive in tumorigenic cell lines which suppress major histocompatibility complex class I genes
RL Mol. Cell. Biol. 10:4100-4109 (1990).
RN [4]; RE0002491.
RX PUBMED: 2247438.
RA Rustgi A. K., van't Veer L., Bernards R.
RT Two genes encode factors with NF-kappaB- and H2TF1-like DNA-binding properties
RL Proc. Natl. Acad. Sci. USA 87:8707-8710 (1990).
RN [5]; RE0054086.
RX PUBMED: 8939960.
RA Diaz-Guerra M. J., Velasco M., Martin-Sanz P., Bosca L.
RT Evidence for common mechanisms in the transcriptional control of type II nitric oxide synthase in isolated hepatocytes. Requirement of NF-kappaB activation after stimulation with bacterial cell wall products and phorbol esters.
RL J. Biol. Chem. 271:30114-30120 (1996).
RN [6]; RE0052350.
RX PUBMED: 11134901.
RA Ramon O., Wong H. K., Joyeux M., Riondel J., Halimi S., Ravanat J. L., Favier A., Cadet J., Faure P.
RT 2'-deoxyguanosine oxidation is associated with decrease in the DNA-binding activity of the transcription factor Sp1 in liver and kidney from diabetic and insulin-resistant rats.
RL Free Radic. Biol. Med. 30:107-118 (2001).
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