AC T00655
XX
ID T00655
XX
DT 15.10.1992 (created); ewi.
DT 31.10.2011 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA POU3F1
XX
SY Oct-6; Octamer binding factor 6; SCIP (rat); Tst-1 (rat).
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G009112 POU3F1; HGNC: POU3F1.
XX
CL C0007; POU.
XX
SZ 448 AA; 45.3 kDa (cDNA) (calc.).
XX
SQ MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGA
SQ GHPVGLAHPQWLPTGGGGGGDWAGAHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAH
SQ AGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGA
SQ GPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGE
SQ HSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSF
SQ KNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPK
SQ PSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGG
SQ ASPPSAPPPPPPAALHHHHHHTLPGSVQ
XX
SC translated from EMBL #L26494
XX
FT 244 318 
PF00157; Pou domain - N-terminal to homeobox domain.
FT 244 318 
SM00352; pou.
FT 334 394 
PS50071; HOMEOBOX_2.
FT 334 396 
PS50550; POU_HOMEODOMAIN.
FT 336 398 
SM00389; HOX_1.
FT 337 393 
PF00046; Homeobox domain.
XX
CP B-cells.
XX
FF able to suppress gene expression, via indirect interaction, independent of a functional POU homeo domain [3];
XX
MX M00795 V$OCT_Q6.
MX M07331 V$POU3F1_Q2.
MX M03842 V$POU3F1_Q6.
MX M00133 V$TST1_01.
MX M01316 V$TST1_02.
XX
BS R01176.
BS R73937.
BS R02228.
BS R04725.
XX
DR TRANSPATH: MO000046008.
DR TRANSCOMPEL: C00146.
DR EMBL: L26494; HSOCT6A.
DR EMBL: Z18284; HSOCT6TR.
DR UniProtKB: Q03052; OCT6_HUMAN.
XX
RN [1]; RE0002117.
RX PUBMED: 2216722.
RA Schreiber E., Harshman K., Kemler I., Malipiero U., Schaffner W., Fontana A.
RT Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins
RL Nucleic Acids Res. 18:5495-5503 (1990).
RN [2]; RE0004406.
RX PUBMED: 8451175.
RA Tobler A., Schreiber E., Fontana A.
RT The human Oct-6 POU transcription factor lacks the first 50 amino acids of its murine counterpart
RL Nucleic Acids Res. 21:1043-1043 (1993).
RN [3]; RE0024541.
RX PUBMED: 8663077.
RA Welter J. F., Gali H., Crish J. F., Eckert R. L.
RT Regulation of human involucrin promoter activity by POU domain proteins.
RL J. Biol. Chem. 271:14727-14733 (1996).
XX
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