AC T00698
AS T01660.
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ID T00698
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DT 15.10.1992 (created); ewi.
DT 08.01.2009 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA PR
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SY NR3C3; PR; progesterone receptor.
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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GE G000072 PGR.
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CL C0002; CC (rec); 2.1.1.1.3.
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SF alternative upstream translation initiation (+127 AA) leads to isoform B [15] [6];
SF alternative translation initiation (-128 AA) leads to isoform A [15] [6];
SF 2nd zinc finger: NLS (nuclear localization signal);
SF weak hormone-inducible NLS within hormone-binding domain [4];
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FF activator or repressor in response to progesterone;
FF isoforms A and B differentially activate the progesterone target genes [19];
FF activator or repressor in response to progesterone;
FF isoforms A and B differentially activate the progesterone target genes [19];
FF no masking of NLSs by hormone-binding domain;
FF cooperative PR binding to adjacent PREs mediates synergistic activation [2] [3];
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MX M00954 V$PR_01.
MX M00957 V$PR_02.
MX M00960 V$PR_Q2.
MX M03799 V$PR_Q6.
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BS R02234.
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DR TRANSPATH: MO000021451.
DR UniProtKB: P07812; PRGR_CHICK.
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RN [1]; RE0000128.
RX PUBMED: 3167984.
RA Tsai S. Y., Carlstedt-Duke J., Weigel N. L., Dahlmann K., Gustafsson J.-A., Tsai M.-J., O'Malley B. W.
RT Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation
RL Cell 55:361-369 (1988).
RN [2]; RE0000129.
RX PUBMED: 2566384.
RA Tsai S. Y., Tsai M.-J., O'Malley B. W.
RT Cooperative Binding of Steroid Hormone Receptors Contribute to Transcriptional Synergism at Target Enhancer Elements
RL Cell 57:443-448 (1989).
RN [3]; RE0000156.
RX PUBMED: 2153462.
RA Klein-Hitpass L., Tsai S. Y., Weigel N. L., Allan G. F., Riley D., Rodriguez R., Schrader W. T., Tsai M.-J., O'Malley B. W.
RT The Progesterone Receptor Stimulates Cell-Free Transcription by Enhancing the Formation of a Stable Preinitiation Complex
RL Cell 60:247-257 (1990).
RN [4]; RE0000304.
RX PUBMED: 1327748.
RA Ylikomi T., Bocquel M. T., Berry M., Gronemeyer H., Chambon P.
RT Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors
RL EMBO J. 11:3681-3694 (1992).
RN [5]; RE0000388.
RX PUBMED: 2540961.
RA Eul J., Meyer M. E., Tora L., Bocquel M. T., Quirin-Stricker C., Chambon P., Gronemeyer H.
RT Expression of active hormone and DNA-binding domains of the chicken progesterone receptor in E. coli
RL EMBO J. 8:83-90 (1989).
RN [6]; RE0000900.
RX PUBMED: 2760059.
RA Conneely O. M., Kettelberger D. M., Tsai M.-J., Schrader W. T., O'Malley B. W.
RT The Chicken Progesterone Receptor A and B Isoforms Are Products of an Alternate Translation Initiation Event
RL J. Biol. Chem. 264:14062-14064 (1989).
RN [7]; RE0000966.
RX PUBMED: 1990008.
RA Turcotte B., Meyer M.-E., Bellard M., Dretzen G., Gronemeyer H., Chambon P.
RT Control of transcription of the chicken progesterone receptor gene
RL J. Biol. Chem. 266:2582-2589 (1991).
RN [8]; RE0001835.
RX PUBMED: 3185713.
RA Biedenkapp H., Borgmeyer U., Sippel A., Klempnauer K.-H.
RT Viral myb oncogene encodes a sequence-specific DNA-binding activity
RL Nature 335:835-837 (1988).
RN [9]; RE0002323.
RX PUBMED: 3458241.
RA von der Ahe D., Renoir J.-M., Buchou T., Baulieu E.-E., Beato M.
RT Receptors for glucocorticosteroid and progesterone recognize distinct features of a DNA regulatory element
RL Proc. Natl. Acad. Sci. USA 83:2817-2821 (1986).
RN [10]; RE0002359.
RX PUBMED: 2426697.
RA Jeltsch J. M., Krozowski Z., Quirin-Stricker C., Gronemeyer H., Simson R. J., Garnier J. M., Krust A., Jacob F., Chambon P.
RT Cloning of the chicken progesterone receptor
RL Proc. Natl. Acad. Sci. USA 83:5424-5428 (1986).
RN [11]; RE0002635.
RX PUBMED: 2426779.
RA Conneely O. M., Sullivan W. P., Toft D. O., Birnbaumer M., Cook R. G., Maxwell B. L., Zarucki-Schulz T., Greene G. L., Schrader W. T., O'Malley B. W.
RT Molecular cloning of the chicken progesterone receptor
RL Science 233:767-770 (1986).
RN [12]; RE0003732.
RX PUBMED: 7688746.
RA Smith D. F., Baggenstoss B. A., Marion T. N., Rimerman R. A.
RT Two FBKP-related proteins are associated with progesterone receptor coplexes
RL J. Biol. Chem. 268:18365-18371 (1993).
RN [13]; RE0003733.
RX PUBMED: 2779568.
RA Kost S. L., Smith D. F., Sullivan W. P., Welch W. J., Toft D. O.
RT Binding of heat shock proteins to the avian progesterone receptor
RL Mol. Cell. Biol. 9:3829-3838 (1989).
RN [14]; RE0003734.
RX PUBMED: 2914922.
RA Radanyi C., Renoir J.-M., Sabbah M., Baulieu E.-E.
RT Chick heat-shock protein of Mr=90.000, free or released from progesterone receptor, is in a dimeric form
RL J. Biol. Chem. 264:2568-2573 (1989).
RN [15]; RE0003736.
RX PUBMED: 2303488.
RA Jeltsch J.-M., Turcotte B., Garnier J.-M., Lerouge T., Krozowski Z., Gronemeyer H., Chambon P.
RT Characterization of multiple mRNA's originating from chicken progesterone receptor gene
RL J. Biol. Chem. 265:3967-3974 (1990).
RN [16]; RE0003737.
RX PUBMED: 3283939.
RA Evans R. M.
RT The steroid and thyroid hormone receptor superfamily
RL Science 240:889-895 (1988).
RN [17]; RE0003742.
RX PUBMED: 1939158.
RA Schowalter D. P., Sullivan W. P., Maihle N. J., Dobson A. D. W., Conneely O. M., O'Malley B. W., Toft D. O.
RT Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins
RL J. Biol. Chem. 266:21165-21173 (1991).
RN [18]; RE0003744.
RX PUBMED: 2303491.
RA Smith D. F., Faber L. E., Toft D. O.
RT Purification of unactivated progesterone receptor and identification of novel receptor-associated proteins
RL J. Biol. Chem. 265:3996-4003 (1990).
RN [19]; RE0003747.
RX PUBMED: 2835683.
RA Tora L., Gronemeyer H., Turcotte B., Gaub M.-P., Chambon P.
RT The N-terminal region of the chicken progesterone receptor specifies target gene activation
RL Nature 333:185-188 (1988).
RN [20]; RE0003749.
RX PUBMED: 5017767.
RA Schrader W. T., O'Malley B. W.
RT Progesterone-binding components of chick oviduct
RL J. Biol. Chem. 247:51-59 (1972).
RN [21]; RE0003791.
RX PUBMED: 3888986.
RA Gronemeyer H., Govindan M. V., Chambon P.
RT Immunological similarity between the chick oviduct progesterone receptor forms A and B
RL J. Biol. Chem. 260:6916-6925 (1985).
RN [22]; RE0025703.
RX PUBMED: 11809754.
RA Hernandez M. P., Chadli A., Toft D. O.
RT HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor.
RL J. Biol. Chem. 277:11873-81 (2002).
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