TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T00698 AS T01660. XX ID T00698 XX DT 15.10.1992 (created); ewi. DT 08.01.2009 (updated); mkl. CO Copyright (C), QIAGEN. XX FA PR XX SY NR3C3; PR; progesterone receptor. XX OS chick, Gallus gallus OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae XX GE G000072 PGR. XX CL C0002; CC (rec); 2.1.1.1.3. XX SF alternative upstream translation initiation (+127 AA) leads to isoform B [15] [6]; SF alternative translation initiation (-128 AA) leads to isoform A [15] [6]; SF 2nd zinc finger: NLS (nuclear localization signal); SF weak hormone-inducible NLS within hormone-binding domain [4]; XX FF activator or repressor in response to progesterone; FF isoforms A and B differentially activate the progesterone target genes [19]; FF activator or repressor in response to progesterone; FF isoforms A and B differentially activate the progesterone target genes [19]; FF no masking of NLSs by hormone-binding domain; FF cooperative PR binding to adjacent PREs mediates synergistic activation [2] [3]; XX MX M00954 V$PR_01. MX M00957 V$PR_02. MX M00960 V$PR_Q2. MX M03799 V$PR_Q6. XX BS R02234. XX DR TRANSPATH: MO000021451. DR UniProtKB: P07812; PRGR_CHICK. XX RN [1]; RE0000128. RX PUBMED: 3167984. RA Tsai S. Y., Carlstedt-Duke J., Weigel N. L., Dahlmann K., Gustafsson J.-A., Tsai M.-J., O'Malley B. W. RT Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation RL Cell 55:361-369 (1988). RN [2]; RE0000129. RX PUBMED: 2566384. RA Tsai S. Y., Tsai M.-J., O'Malley B. W. RT Cooperative Binding of Steroid Hormone Receptors Contribute to Transcriptional Synergism at Target Enhancer Elements RL Cell 57:443-448 (1989). RN [3]; RE0000156. RX PUBMED: 2153462. RA Klein-Hitpass L., Tsai S. Y., Weigel N. L., Allan G. F., Riley D., Rodriguez R., Schrader W. T., Tsai M.-J., O'Malley B. W. RT The Progesterone Receptor Stimulates Cell-Free Transcription by Enhancing the Formation of a Stable Preinitiation Complex RL Cell 60:247-257 (1990). RN [4]; RE0000304. RX PUBMED: 1327748. RA Ylikomi T., Bocquel M. T., Berry M., Gronemeyer H., Chambon P. RT Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors RL EMBO J. 11:3681-3694 (1992). RN [5]; RE0000388. RX PUBMED: 2540961. RA Eul J., Meyer M. E., Tora L., Bocquel M. T., Quirin-Stricker C., Chambon P., Gronemeyer H. RT Expression of active hormone and DNA-binding domains of the chicken progesterone receptor in E. coli RL EMBO J. 8:83-90 (1989). RN [6]; RE0000900. RX PUBMED: 2760059. RA Conneely O. M., Kettelberger D. M., Tsai M.-J., Schrader W. T., O'Malley B. W. RT The Chicken Progesterone Receptor A and B Isoforms Are Products of an Alternate Translation Initiation Event RL J. Biol. Chem. 264:14062-14064 (1989). RN [7]; RE0000966. RX PUBMED: 1990008. RA Turcotte B., Meyer M.-E., Bellard M., Dretzen G., Gronemeyer H., Chambon P. RT Control of transcription of the chicken progesterone receptor gene RL J. Biol. Chem. 266:2582-2589 (1991). RN [8]; RE0001835. RX PUBMED: 3185713. RA Biedenkapp H., Borgmeyer U., Sippel A., Klempnauer K.-H. RT Viral myb oncogene encodes a sequence-specific DNA-binding activity RL Nature 335:835-837 (1988). RN [9]; RE0002323. RX PUBMED: 3458241. RA von der Ahe D., Renoir J.-M., Buchou T., Baulieu E.-E., Beato M. RT Receptors for glucocorticosteroid and progesterone recognize distinct features of a DNA regulatory element RL Proc. Natl. Acad. Sci. USA 83:2817-2821 (1986). RN [10]; RE0002359. RX PUBMED: 2426697. RA Jeltsch J. M., Krozowski Z., Quirin-Stricker C., Gronemeyer H., Simson R. J., Garnier J. M., Krust A., Jacob F., Chambon P. RT Cloning of the chicken progesterone receptor RL Proc. Natl. Acad. Sci. USA 83:5424-5428 (1986). RN [11]; RE0002635. RX PUBMED: 2426779. RA Conneely O. M., Sullivan W. P., Toft D. O., Birnbaumer M., Cook R. G., Maxwell B. L., Zarucki-Schulz T., Greene G. L., Schrader W. T., O'Malley B. W. RT Molecular cloning of the chicken progesterone receptor RL Science 233:767-770 (1986). RN [12]; RE0003732. RX PUBMED: 7688746. RA Smith D. F., Baggenstoss B. A., Marion T. N., Rimerman R. A. RT Two FBKP-related proteins are associated with progesterone receptor coplexes RL J. Biol. Chem. 268:18365-18371 (1993). RN [13]; RE0003733. RX PUBMED: 2779568. RA Kost S. L., Smith D. F., Sullivan W. P., Welch W. J., Toft D. O. RT Binding of heat shock proteins to the avian progesterone receptor RL Mol. Cell. Biol. 9:3829-3838 (1989). RN [14]; RE0003734. RX PUBMED: 2914922. RA Radanyi C., Renoir J.-M., Sabbah M., Baulieu E.-E. RT Chick heat-shock protein of Mr=90.000, free or released from progesterone receptor, is in a dimeric form RL J. Biol. Chem. 264:2568-2573 (1989). RN [15]; RE0003736. RX PUBMED: 2303488. RA Jeltsch J.-M., Turcotte B., Garnier J.-M., Lerouge T., Krozowski Z., Gronemeyer H., Chambon P. RT Characterization of multiple mRNA's originating from chicken progesterone receptor gene RL J. Biol. Chem. 265:3967-3974 (1990). RN [16]; RE0003737. RX PUBMED: 3283939. RA Evans R. M. RT The steroid and thyroid hormone receptor superfamily RL Science 240:889-895 (1988). RN [17]; RE0003742. RX PUBMED: 1939158. RA Schowalter D. P., Sullivan W. P., Maihle N. J., Dobson A. D. W., Conneely O. M., O'Malley B. W., Toft D. O. RT Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins RL J. Biol. Chem. 266:21165-21173 (1991). RN [18]; RE0003744. RX PUBMED: 2303491. RA Smith D. F., Faber L. E., Toft D. O. RT Purification of unactivated progesterone receptor and identification of novel receptor-associated proteins RL J. Biol. Chem. 265:3996-4003 (1990). RN [19]; RE0003747. RX PUBMED: 2835683. RA Tora L., Gronemeyer H., Turcotte B., Gaub M.-P., Chambon P. RT The N-terminal region of the chicken progesterone receptor specifies target gene activation RL Nature 333:185-188 (1988). RN [20]; RE0003749. RX PUBMED: 5017767. RA Schrader W. T., O'Malley B. W. RT Progesterone-binding components of chick oviduct RL J. Biol. Chem. 247:51-59 (1972). RN [21]; RE0003791. RX PUBMED: 3888986. RA Gronemeyer H., Govindan M. V., Chambon P. RT Immunological similarity between the chick oviduct progesterone receptor forms A and B RL J. Biol. Chem. 260:6916-6925 (1985). RN [22]; RE0025703. RX PUBMED: 11809754. RA Hernandez M. P., Chadli A., Toft D. O. RT HSP40 binding is the first step in the HSP90 chaperoning pathway for the progesterone receptor. RL J. Biol. Chem. 277:11873-81 (2002). XX //