
AC T00789
XX
ID T00789
XX
DT 03.11.1992 (created); ewi.
DT 27.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA Tll
XX
SY NR2E2; Tailless; TLL.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
GE G009908 tll.
XX
HO vertebrate Tll/Txl.
XX
CL C0002; CC (rec).
XX
SZ 452 AA; 50.5 kDa (cDNA) (calc.).
XX
SQ MQSSEGSPDMMDQKYNSVRLSPAASSRILYHVPCKVCRDHSSGKHYGIYACDGCAGFFKR
SQ SIRRSRQYVCKSQKQGLCVVDKTHRNQCRACRLRKCFEVGMNKDAVQHERGPRNSTLRRH
SQ MAMYKDAMMGAGEMPQIPAEILMNTAALTGFPGVPMPMPGLPQRAGHHPAHMAAFQPPPS
SQ AAAVLDLSVPRVPHHPVHQGHHGFFSPTAAYMNALATRALPPTPPLMAAEHIKETAAEHL
SQ FKNVNWIKSVRAFTELPMPDQLLLLEESWKEFFILAMAQYLMPMNFAQLLFVYESENANR
SQ EIMGMVTREVHAFQEVLNQLCHLNIDSTEYECLRAISLFRKSPPSASSTEDLANSSILTG
SQ SGSPNSSASAESRGLLESGKVAAMHNDARSALHNYIQRTHPSQPMRFQTLLGVVQLMHKV
SQ SSFTIEELFFRKTIGDITIVRLISDMYSQRKI
XX
SC Swiss-Prot#P18102
XX
FT 31 104
SM00399; c4gold.
FT 31 108
PS51030; NUCLEAR_REC_DBD_2.
FT 32 109
PF00105; Zinc finger, C4 type (two domains).
FT 173 447
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 234 421
SM00430; holi.
FT 237 446
PF00104; Ligand-binding domain of nuclear hormon.
XX
SF tll mutants lack abdominal segment 8 and the telson and show skeletal abnormalities in the anterior [3];
XX
CP (embryonic) early: anterior and posterior domain, later: anterior -> developing brain, temporal in the PNS [3].
XX
FF repressor of Krueppel expression;
FF activator of hairy in stripe 7;
XX
MX M03155 I$TLL_01.
MX M00679 I$TLL_Q6.
XX
BS R17490.
BS R17491.
BS R17691.
BS R17692.
BS R17693.
BS R17694.
BS R17695.
BS R17696.
BS R17697.
BS R17698.
BS R17699.
BS R17440.
BS R17450.
BS R17638.
BS R17644.
BS R17648.
BS R17658.
BS R17665.
BS R04959.
BS R04960.
BS R04961.
BS R04962.
BS R02274.
BS R02276.
BS R02277.
BS R02279.
BS R02281.
BS R02282.
BS R02285.
BS R17352.
BS R17355.
BS R17361.
BS R17577.
BS R17583.
XX
DR TRANSPATH: MO000025174.
DR EMBL: M34639;
DR UniProtKB: P18102;
DR FLYBASE: FBgn0003720; tll.
XX
RN [1]; RE0002689.
RX PUBMED: 1348871.
RA Hoch M., Gerwin N., Taubert H., Jaeckle H.
RT Competition for overlapping sites in the regulatory region of the Drosophila gene Krueppel
RL Science 256:94-97 (1992).
RN [2]; RE0002801.
RX PUBMED: 1902805.
RA Riddihough G., Ish-Horowicz D.
RT Individual stripe regulatory elements in the Drosophila hairy promoter respond to maternal, gap, and pair-rule genes
RL Genes Dev. 5:840-854 (1991).
RN [3]; RE0006664.
RX PUBMED: 2364433.
RA Pignoni F., Baldarelli R. M., Steingrimsson E., Diaz R. J., Patapoutian A., Merriam J. R., Lengyel J. A.
RT The Drosophila Gene tailless is Expressed at the Embryonic Termini and Is a Member of the Steroid Receptor Superfamily
RL Cell 62:151-163 (1990).
RN [4]; RE0013625.
RX PUBMED: 10219237.
RA Nuclear Receptors Nomenclature Committee.
RT A unified nomenclature system for the nuclear receptor superfamily
RL Cell 97:161-163 (1999).
XX
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