AC T00836
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ID T00836
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DT 28.01.1993 (created); hse.
DT 11.03.2010 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA T3R-alpha1
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SY c-ErbA; NR1A1; T3R; THRA; thyroid hormone receptor; TR.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002946 Thra.
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CL C0002; CC (rec); 2.1.2.2.1.1.
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SZ 410 AA; 46.8 kDa (calc.), 46 kDa
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SQ MEQKPSKVECGSDPEENSARSPDGKRKRKNGQCPLKSSMSGYIPSYLDKDEQCVVCGDKA
SQ TGYHYRCITCEGCKGFFRRTIQKNLHPTYSCKYDSCCVIDKITRNQCQLCRFKKCIAVGM
SQ AMDLVLDDSKRVAKRKLIEQNRERRRKEEMIRSLQQRPEPTPEEWDLIHVATEAHRSTNA
SQ QGSHWKQRRKFLPDDIGQSPIVSMPDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFS
SQ ELPCEDQIILLKGCCMEIMSLRAAVRYDPESDTLTLSGEMAVKREQLKNGGLGVVSDAIF
SQ ELGKSLSAFNLDDTEVALLQAVLLMSTDRSGLLCVDKIEKSQEAYLLAFEHYVNHRKHNI
SQ PHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFEDQEV
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SC translated from EMBL #X51983
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FT 50 123 SM00399; c4gold.
FT 50 127 PS51030; NUCLEAR_REC_DBD_2.
FT 51 128 PF00105; Zinc finger, C4 type (two domains).
FT 83 329 PF00478; IMP dehydrogenase / GMP reductase domai.
FT 220 378 SM00430; holi.
FT 223 404 PF00104; Ligand-binding domain of nuclear hormon.
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SF phosphorylation;
SF another splice variant produced from the same gene is T3R-alpha2 T01173;
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FF member of the steroid hormone receptor superfamily;
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IN T00719 NR1B1-isoform1; human, Homo sapiens.
IN T00720 RAR-gamma; human, Homo sapiens.
IN T00716 RAR; monkey, Cercopithecus aethiops.
IN T00717 RAR; mouse, Mus musculus.
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MX M01724 V$T3RALPHA_Q6.
MX M00963 V$T3R_Q6.
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BS R30669.
BS R29414.
BS R72843.
BS R72242.
BS R72241.
BS R03523.
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DR TRANSPATH: MO000025207.
DR EMBL: X51983;
DR UniProtKB: P63058-2;
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RN [1]; RE0001498.
RX PUBMED: 1922030.
RA Lazar M. A., Berrodin T. J., Harding H. P.
RT Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor
RL Mol. Cell. Biol. 11:5005-5015 (1991).
RN [2]; RE0001752.
RX PUBMED: 2172797.
RA Forman B. M., Samuels H. H.
RT Interactions among a subfamily of nuclear hormone receptors: the regulatory zipper model
RL Mol. Endocrinol. 4:1293-1301 (1990).
RN [3]; RE0002738.
RX PUBMED: 2159385.
RA Baniahmad A., Steiner C., Koehne A. C., Renkawitz R.
RT Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site
RL Cell 61:505-514 (1990).
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