AC T00991
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ID T00991
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DT 08.12.1993 (created); ewi.
DT 03.12.2014 (updated); sup.
CO Copyright (C), QIAGEN.
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FA PPARalpha
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SY NR1C1; peroxisome proliferator-activated receptor; peroxisome proliferator-activated receptor alpha; PPAR; PPARalpha.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014219 Ppara.
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CL C0002; CC (rec); 2.1.2.5.1.
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FF activated by unsaturated fatty acids, arachidonic acid, linoleic acid, clofibric acid, nafenopin, WY-14,643, leading to enhanced peroxisome proliferation;
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IN T05962 NCOR1; rat, Rattus norvegicus.
IN T16712 NFATc4; rat, Rattus norvegicus.
IN T04383 RXR-alpha; rat, Rattus norvegicus.
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MX M00242 V$PPARA_01.
MX M00518 V$PPARA_02.
MX M01282 V$PPARA_Q6.
MX M00763 V$PPARDR1_Q2.
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BS R07672.
BS R01193.
BS R18613.
BS R02233.
BS R04600.
BS R15791.
BS R60316.
BS R23741.
BS R28308.
BS R34126.
BS R34127.
BS R34128.
BS R03931.
BS R60314.
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DR TRANSPATH: MO000025324.
DR UniProtKB: P37230;
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RN [1]; RE0002534.
RX PUBMED: 1316614.
RA Goettlicher M., Widmark E., Li Q., Gustafsson J. A.
RT Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor
RL Proc. Natl. Acad. Sci. USA 89:4653-4657 (1992).
RN [2]; RE0025706.
RX PUBMED: 11903058.
RA Krogsdam A. M., Nielsen C. A., Neve S., Holst D., Helledie T., Thomsen B., Bendixen C., Mandrup S., Kristiansen K.
RT Nuclear receptor corepressor-dependent repression of peroxisome-proliferator-activated receptor delta-mediated transactivation.
RL Biochem. J. 363:157-65 (2002).
RN [3]; RE0047997.
RX PUBMED: 15870285.
RA Ki S. H., Cho I. J., Choi D. W., Kim S. G.
RT Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression.
RL Mol. Cell. Biol. 25:4150-4165 (2005).
RN [4]; RE0050850.
RX PUBMED: 8828512.
RA Shalev A., Siegrist-Kaiser C. A., Yen P. M., Wahli W., Burger A. G., Chin W. W., Meier C. A.
RT The peroxisome proliferator-activated receptor alpha is a phosphoprotein: regulation by insulin.
RL Endocrinology 137:4499-4502 (1996).
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