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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T00996 XX ID T00996 XX DT 25.01.1994 (created); ewi. DT 16.11.2012 (updated); sup. CO Copyright (C), QIAGEN. XX FA SRY XX SY sex determining region of Chr Y; SRY; TDF; TDY; testis-determining factor. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G000605 Sry. XX CL C0015; HMG; 4.1.1.1.1. XX SF induces even larger bending angles in two different binding sequences than the human factor (85 and 60 degree vs. 60 and 30 degree, resp.) [4]; XX FF testis-determining factor [2]; XX MX M08899 V$SOX_Q4. MX M01014 V$SOX_Q6. MX M00148 V$SRY_01. MX M00160 V$SRY_02. MX M02917 V$SRY_05. MX M02813 V$SRY_07. MX M03854 V$SRY_Q6. XX BS R40772. BS R21694. BS R21718. BS R04588. BS R04593. XX DR TRANSPATH: MO000046038. DR UniProtKB: Q05738; SRY_MOUSE. XX RN [1]; RE0001905. RX PUBMED: 1956382. RA Nasrin N., Buggs C., Kong X. F., Carnazza J., Goebl M., Alexander-Bridges M. RT DNA-binding properties of the product of the testis-determining gene and a related protein RL Nature 354:317-320 (1991). RN [2]; RE0004346. RX PUBMED: 2374589. RA Gubbay J., Collignon J., Koopman P., Capel B., Economou A., Muensterberg A., Vivian N., Goodfellow P., Lovell-Badge R. RT A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes RL Nature 346:245-250 (1990). RN [3]; RE0005077. RX PUBMED: 8012385. RA Coward P., Nagai K., Chen D., Thomas H. D., Nagamine C. M., Lau Y. F. RT Polymorphism of a CAG trinucleotide repeat within Sry correlates with B6.YDom sex reversal RL Nat. Genet. 6:245-250 (1994). RN [4]; RE0005078. RX PUBMED: 8159753. RA Giese K., Pagel J., Grosschedl R. RT Distinct DNA-binding properties of the high mobility group domain of murine and human SRY sex-determining factors RL Proc. Natl. Acad. Sci. USA 91:3368-3372 (1994). RN [5]; RE0005079. RX PUBMED: 1349578. RA Kunieda T., Toyoda Y. RT Nucleotide sequence of mouse Sry gene is different between Y chromosome originating from Mus musculus musculus and Mus musculus domesticus RL Genomics 13:236-237 (1992). RN [6]; RE0005080. RX PUBMED: 1518820. RA Gubbay J., Vivian N., Economou A., Jackson D., Goodfellow P., Lovell-Badge R. RT Inverted repeat structure of the Sry locus in mice RL Proc. Natl. Acad. Sci. USA 89:7953-7957 (1992). XX //