AC T01019
XX
ID T01019
XX
DT 19.02.1994 (created); ewi.
DT 13.07.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA Elf-1
XX
SY CP2 (human, mouse); Elf-1; grainyhead; grh; NTF-1.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
GE G018698 grh.
XX
HO CP2 (human, mouse); LBP-32 (human); MGR (mouse).
XX
CL C0051; Grainyhead.
XX
SZ 1333 AA; 143.9 kDa (cDNA) (calc.).
XX
SQ MSTSTATTSVITSNELSLSGHAHGHGHAHQLHQHTHSRLGVGVGVGILSDASLSPIQQGS
SQ GGHSGGGNTNSSPLAPNGVPLLTTMHRSPDSPQPELATMTNVNVLDLHTDNSKLYDKEAV
SQ FIYETPKVVMPADGGGGNNSDEGHAIDARIAAQMGNQAQQQQQQQQQTEHQPLAKIEFDE
SQ NQIIRVVGPNGEQQQIISREIINGEHHILSRNEAGEHILTRIVSDPSKLMPNDNAVATAM
SQ YNQAQKMNNDHGQAVYQTSPLPLDASVLHYSGGNDSNVIKTEADIYEDHKKHAAAAAAAA
SQ GGGSIIYTTSDPNGVNVKQLPHLTVPQKLDPDLYQADKHIDLIYNDGSKTVIYSTTDQKS
SQ LEIYSGGDIGSLVSDGQVVVQAGLPYATTTGAGGQPVYIVADGALPAGVEEHLQSGKLNG
SQ QTTPIDVSGLSQNEIQGFLLGSHPSSSATVSTTGVVSTTTISHHQQQQQQQQQQQQQQQQ
SQ QHQQQQQHPGDIVSAAGVGSTGSIVSSAAQQQQQQQLISIKREPEDLRKDPKNGNIAGAA
SQ TANGPGSVITQKILHVDAPTASEADRPSTPSSSINSTENTESDSQSVSGSESGSPGARTT
SQ ATLEMYATTGGTQIYLQTSHPSTASGAGGGAGPAGAAGGGGVSMQAQSPSPGPYITANDY
SQ GMYTASRLPPGPPPTSTTTFIAEPSYYREYFAPDGQGGYVPASTRSLYGDVDVSVSQPGG
SQ VVTYEGRFAGSVPPPATTTVLTSVHHHQQQQQQQQQHQQQQQQQQHHQQQQHHSQDGKSN
SQ GGATPLYAKAITAAGLTVDLPSPDSGIGTDAITPRDQTNIQQSFDYTELCQPGTLIDANG
SQ SIPVSVNSIQQRTAVHGSQNSPTTSLVDTSTNGSTRSRPWHDFGRQNDADKIQIPKIFTN
SQ VGFRYHLESPISSSQRREDDRITYINKGQFYGITLEYVHDAEKPIKNTTVKSVIMLMFRE
SQ EKSPEDEIKAWQFWHSRQHSVKQRILDADTKNSVGLVGCIEEVSHNAIAVYWNPLESSAK
SQ INIAVQCLSTDFSSQKGVKGLPLHVQIDTFEDPRDTAVFHRGYCQIKVFCDKGAERKTRD
SQ EERRAAKRKMTATGRKKLDELYHPVTDRSEFYGMQDFAKPPVLFSPAEDMEKVGQLGIGA
SQ ATGMTFNPLSNGNSNSNSHSSLQSFYGHETDSPDLKGASPFLLHGQKVATPTLKFHNHFP
SQ PDMQTDKKDHILDQNMLTSTPLTDFGPPMKRGRMTPPTSERVMLYVRQENEEVYTPLHVV
SQ PPTTIGLLNAIENKYKISTTSINNIYRTNKKGITAKIDDDMISFYCNEDIFLLEVQQIED
SQ DLYDVTLTELPNQ
XX
SC Swiss-Prot#P13002
XX
FT 113 482 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 600 823 
PF04516; CP2 transcription factor.
XX
SF dimer, both in solution and upon DNA binding [4];
XX
CP (embryo).
XX
FF embryonal regulator of genes involved in epidermal differentiation;
FF regulator of developmental control genes: Ultrabithorax, tailless, decapentaplegic;
XX
MX M00110 I$ELF1_01.
MX M00951 I$GRH_01.
XX
BS R06703.
BS R06704.
BS R06705.
BS R06706.
BS R06707.
BS R00481.
BS R00482.
BS R00483.
BS R00484.
BS R01522.
BS R04576.
XX
DR TRANSPATH: MO000025346.
DR EMBL: X15657;
DR UniProtKB: P13002;
DR FLYBASE: FBgn0004586; grh.
XX
RN [1]; RE0000599.
RX PUBMED: 2606344.
RA Dynlacht B. D., Attardi L. D., Admon A., Freeman M., Tjian R.
RT Functional analysis of NTF-1, a developmentally regulated Drosophila transcription factor that binds neuronal cis elements
RL Genes Dev. 3:1677-1688 (1989).
RN [2]; RE0000778.
RX PUBMED: 1909284.
RA Bray S. J., Kafatos F. C.
RT Developmental function of Elf-1: an essential transcription factor during embryogenesis in Drosophila
RL Genes Dev. 5:1672-1683 (1991).
RN [3]; RE0003055.
RX PUBMED: 2792757.
RA Bray S. J., Burke B., Brown N. H., Hirsh J.
RT Embryonic expression pattern of a family of Drosophila proteins that interact with central nervous system regulatory element
RL Genes Dev. 3:1130-1145 (1989).
RN [4]; RE0023309.
RX PUBMED: 9668115.
RA Shirra M. K., Hansen U.
RT LSF and NTF-1 share a conserved DNA recognition motif yet require different oligomerization states to form a stable protein-DNA complex.
RL J. Biol. Chem. 273:19260-19268 (1998).
RN [5]; RE0023445.
RX PUBMED: 12888489.
RA Venkatesan K., McManus H. R., Mello C. C., Smith T. F., Hansen U.
RT Functional conservation between members of an ancient duplicated transcription factor family, LSF/Grainyhead.
RL Nucleic Acids Res. 31:4304-4316 (2003).
XX
//