AC T01251
XX
ID T01251
XX
DT 25.07.1994 (created); ewi.
DT 08.02.2008 (updated); smt.
CO Copyright (C), QIAGEN.
XX
FA res2
XX
SY partner of cdc10; pct1; res2.
XX
OS fission yeast, Schizosaccharomyces pombe
OC Eukaryota; Fungi; Ascomycota; Archiascomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
HO SWI4 (S. cer.), res1 (S. pombe).
XX
SZ 657 AA; 73.7 kDa (gene) (calc.).
XX
SQ MAPRSSAVHVAVYSGVEVYECFIKGVSVMRRRRDSWLNATQILKVADFDKPQRTRVLERQ
SQ VQIGAHEKVQGGYGKYQGTWVPFQRGVDLATKYKVDGIMSPILSLDIDEGKAIAPKKKQT
SQ KQKKPSVRGRRGRKPSSLSSSTLHSVNEKQPNSSISPTIESSMNKVNLPGAEEQVSATPL
SQ PASPNALLSPNDNTIKPVEELGMLEAPLDKYEESLLDFFLHPEEGRIPSFLYSPPPDFQV
SQ NSVIDDDGHTSLHWACSMGHIEMIKLLLRANADIGVCNRLSQTPLMRSVIFTNNYDCQTF
SQ GQVLELLQSTIYAVDTNGQSIFHHIVQSTSTPSKVAAAKYYLDCILEKLISIQPFENVVR
SQ LVNLQDSNGDTSLLIAARNGAMDCVNSLLSYNANPSIPNRQRRTASEYLLEADKKPHSLL
SQ QSNSNASHSAFSFSGISPAIISPSCSSHAFVKAIPSISSKFSQLAEEYESQLREKEEDLI
SQ RANRLKQDTLNEISRTYQELTFLQKNNPTYSQSMENLIREAQETYQQLSKRLLIWLEARQ
SQ IFDLERSLKPHTSLSISFPSDFLKKEDGLSLNNDFKKPACNNVTNSDEYEQLINKLTSLQ
SQ ASRKKDTLYIRKLYEELGIDDTVNSYRRLIAMSCGINPEDLSLEILDAVEEALTREK
XX
SC Swiss-Prot#P41412
XX
FT 27 110 
PF02292; APSES domain.
FT 44 478 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 247 276 
SM00248; ANK_2a.
FT 247 279 
PF00023; Ankyrin repeat.
FT 247 279 
PS50088; ANK_REPEAT.
FT 247 400 
PS50297; ANK_REP_REGION.
FT 368 397 
SM00248; ANK_2a.
FT 368 400 
PF00023; Ankyrin repeat.
FT 368 400 
PS50088; ANK_REPEAT.
XX
SF the N-terminal 152 amino acids are sufficient for DNA binding [2];
SF the C-terminal amino acids from 415 to 657 are sufficient for binding to cdc10p T01252 [2];
XX
FF res2p is highly induced during conjugation and strongly depends on cdc10p T01252 for its activity [3];
FF Res2p-Cdc10p complex is activated by pas1p [4];
XX
IN T01252 cdc10; fission yeast, Schizosaccharomyces pombe.
XX
BS R03782.
BS R03783.
BS R03781.
XX
DR EMBL: D17761;
DR EMBL: Z32838;
DR EMBL: Z54285;
DR UniProtKB: P41412;
XX
RN [1]; RE0000781.
RX PUBMED: 7926774.
RA Zhu Y., Takeda T., Nasmyth K., Jones N.
RT pct1+, which encodes a new DNA-binding partner of p85cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe
RL Genes Dev. 8:885-898 (1994).
RN [2]; RE0005999.
RX PUBMED: 9118941.
RA Zhu Y., Takeda T., Whitehall S., Peat N., Jones N.
RT Functional characterization of the fission yeast Start-specific transcription factor Res2
RL EMBO J. 16:1023-1034 (1997).
RN [3]; RE0015615.
RX PUBMED: 8168485.
RA Miyamoto M., Tanaka K., Okayama H.
RT res2+, a new member of the cdc10+/SWI4 family, controls the 'start' of mitotic and meiotic cycles in fission yeast
RL EMBO J. 15:1873-1880 (1994).
RN [4]; RE0015626.
RX PUBMED: 10982385.
RA Tanaka K., Okayama H.
RT A pcl-like cyclin activates the Res2p-Cdc10p cell cycle "Start" transcriptional factor complex in fission yeast
RL Mol. Biol. Cell 11:2845-2862 (2000).
XX
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