AC T01406
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ID T01406
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DT 11.12.1994 (created); ewi.
DT 19.02.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA GABP-beta1
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SY nuclear respiratory factor 2beta1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003951 GABPB1; HGNC: GABPB1.
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SZ 395 AA; 42.5 kDa (cDNA) (calc.), 48 kDa (SDS)
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SQ MSLVDLGKKLLEAARAGQDDEVRILMANGAPFTTDWLGTSPLHLAAQYGHYSTTEVLLRA
SQ GVSRDARTKVDRTPLHMAASEGHASIVEVLLKHGADVNAKDMLKMTALHWATEHNHQEVV
SQ ELLIKYGADVHTQSKFCKTAFDISIDNGNEDLAEILQIAMQNQINTNPESPDTVTIHAAT
SQ PQFIIGPGGVVNLTGLVSSENSSKATDETGVSAVQFGNSSTSVLATLAALAEASAPLSNS
SQ SETPVVATEEVVTAESVDGAIQQVVSSGGQQVITIVTDGIQLGNLHSIPTSGIGQPIIVT
SQ MPDGQQVLTVPATDIAEETVISEEPPAKRQCIEIIENRVESAEIEEREALQKQLDEANRE
SQ AQKYRQQLLKKEQEAEAYRQKLEAMTRLQTNKEAV
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SC translated from EMBL #U13045
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FT 37 66 
SM00248; ANK_2a.
FT 37 69 
PF00023; Ankyrin repeat.
FT 37 69 
PS50088; ANK_REPEAT.
FT 37 156 
PS50297; ANK_REP_REGION.
FT 49 381 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 70 99 
SM00248; ANK_2a.
FT 70 102 
PF00023; Ankyrin repeat.
FT 70 102 
PS50088; ANK_REPEAT.
FT 103 132 
SM00248; ANK_2a.
FT 103 135 
PF00023; Ankyrin repeat.
FT 103 135 PS50088; ANK_REPEAT.
FT 136 166 SM00248; ANK_2a.
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SF splice variants are GABP-beta1 (NRF-2beta2) T01391, NRF-2gamma1 T01407 and GABP-beta2 (NRF-2gamma2) T01392;
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CP broad distribution.
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FF part of the transcriptional activator NRF-2, may have to modulate the DNA-binding to tandem repeat elements;
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MX M00971 V$ETS_Q6.
MX M01876 V$GABPBETA_Q3.
MX M00341 V$GABP_B.
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BS R03472.
BS R03473.
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DR TRANSPATH: MO000025650.
DR EMBL: U13045;
DR UniProtKB: Q06547-1;
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RN [1]; RE0000801.
RX PUBMED: 8383622.
RA Virbasius J. V., Virbasius C.-M. A., Scarpulla R. C.
RT Identity of GABP with NRF-2, a multisubunit activator of cytochrome oxidase expression, reveals a cellular role for an Ets domain activator of viral promoters
RL Genes Dev. 7:380-392 (1993).
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//