AC T01429
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ID T01429
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DT 10.04.1995 (created); ewi.
DT 11.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Sox-5
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SY Sox-5; SRY-related HMG-box gene 5.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006753 Sox5.
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CL C0015; HMG; 4.1.1.4.1.
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SF solution structure similar to that of HMG1 [2];
SF overlapping DNA-binding specificity with SRY [1];
SF binds to AACAAT with KD = 1 nM [2];
SF DNA-binding in a 1:1 stoichiometry does not affect the protein structure, but bends the DNA [2];
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CP post-meiotic germ cells; round spermatids (highest level) [1].
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MX M00042 V$SOX5_01.
MX M02910 V$SOX5_04.
MX M03850 V$SOX5_Q5.
MX M08899 V$SOX_Q4.
MX M01014 V$SOX_Q6.
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BS R27941.
BS R32263.
BS R32264.
BS R32265.
BS R70145.
BS R70149.
BS R70150.
BS R57593.
BS R65143.
BS R21448.
BS R32261.
BS R32262.
BS R04550.
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DR TRANSPATH: MO000025662.
DR UniProtKB: P35710;
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RN [1]; RE0002914.
RX PUBMED: 1396566.
RA Denny P., Swift S., Connor F., Ashworth A.
RT An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding protein
RL EMBO J. 11:3705-3712 (1992).
RN [2]; RE0004358.
RX PUBMED: 8078769.
RA Connor F., Cary P. D., Read C. M., Preston N. S., Driscoll P. C., Denny P., Crane-Robinson C., Ashworth A.
RT DNA binding and bending properties of the postmeiotically expressed Sry-related protein Sox-5
RL Nucleic Acids Res. 22:3339-3346 (1994).
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