AC T01508
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ID T01508
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DT 09.06.1995 (created); ewi.
DT 26.11.2010 (updated); din.
CO Copyright (C), QIAGEN.
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FA PTF
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SY PBP; PSE-binding protein; PSE-binding transcription factor; SNAPc; snRNA activating protein complex.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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SF multisubunit complex of four polypeptides alpha, beta, gamma, delta;
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CP (HeLa).
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FF binds to PSE sequences of snRNA genes transcribed by pol II or by pol III;
FF functionally cooperates with Oct-1 or Oct-2;
FF interacts substoichiometrically with TBP;
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IN T00794 TBP; human, Homo sapiens.
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BS R04275.
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DR TRANSPATH: MO000025722.
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RN [1]; RE0003098.
RX PUBMED: 1535687.
RA Murphy S., Yoon J.-B., Gerster T., Roeder R. G.
RT Oct-1 and Oct-2 potentiate functional interactions of a transcription factor with the proximal sequence element of small nuclear RNA genes
RL Mol. Cell. Biol. 12:3247-3261 (1992).
RN [2]; RE0003815.
RX PUBMED: 8524284.
RA Yoon J.-B., Roeder R. G.
RT Cloning of two proximal sequence element-binding transcription factor subunits (alpha and delta) that are required for transcription of small nuclear RNA genes by RNA polymerase II and III and interact with the TATA-binding protein
RL Mol. Cell. Biol. 16:1-9 (1996).
RN [3]; RE0003832.
RX PUBMED: 8339931.
RA Sadowski C. L., Henry R. W., Lobo S. M., Hernandez N.
RT Targeting TBP to a non-TATA box cis-regulatory element: a TBP-containing complex activates transcription from snRNA promoters through the PSE
RL Genes Dev. 7:1535-1548 (1993).
RN [4]; RE0003833.
RX PUBMED: 7715707.
RA Henry R. W., Sadowski C. L., Kobayashi R., Hernandez N.
RT A TBF-TAF complex required for transcription of human snRNA genes by RNA polymerases II and III
RL Nature 374:653-656 (1995).
RN [5]; RE0003834.
RX PUBMED: 8454634.
RA Wanandi I., Waldschmidt R., Seifart K. H.
RT Mammalian transcription factor PBP. Characterization of its binding properties to the proximal sequence element of U6 genes
RL J. Biol. Chem. 268:6629-6640 (1993).
RN [6]; RE0003835.
RX PUBMED: 1868835.
RA Waldschmidt R., Wanandi I., Seifart K. H.
RT Identification of transcription factors required for the expression of mammalian U6 genes in vitro
RL EMBO J. 10:2595-2603 (1991).
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