AC T01534
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ID T01534
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DT 23.07.1995 (created); hiwi.
DT 05.06.2015 (updated); pro.
CO Copyright (C), QIAGEN.
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FA Myf-5
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SY B130010J22Rik; MYF5; myogenic factor 5.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006453 Myf5.
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CL C0010; bHLH; 1.2.2.1.3.
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CP myogenic cells.
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FF can partly be substituted by and can substitute for MyoD [2];
FF indispensable for normal rib development, probably controlling timely appearance of myotomal cells in early somites [4];
FF first myogenic factor expressed during myogenic differentiation;
FF expression is subjected to negative control by MyoD [3];
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MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M03880 V$MYF5_Q6.
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BS R68123.
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DR TRANSPATH: MO000025746.
DR UniProtKB: P24699;
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RN [1]; RE0003234.
RX PUBMED: 8387507.
RA Winter B., Braun T., Arnold H. H.
RT cAMP-dependent protein kinase represses myogenic differentiation and the activity of the muscle-specific helix-loop-helix transcription factors Myf-5 and MyoD
RL J. Biol. Chem. 13:9869-9878 (1993).
RN [2]; RE0003239.
RX PUBMED: 8269513.
RA Rudnicki M. A., Schnegelsberg P. N. J., Stead R. H., Braun T., Arnold H. H., Jaenisch R.
RT MyoD or Myf-5 is required for the formation of skeletal muscle
RL Cell 75:1351-1359 (1993).
RN [3]; RE0003244.
RX PUBMED: 1330322.
RA Rudnicki M. A., Braun T., Hinuma S., Jaenisch R.
RT Inactivation of MyoD in mice leads to up-regulation of the myogenic HLH gene Myf-5 and results in apparently normal muscle development
RL Cell 71:383-390 (1992).
RN [4]; RE0003262.
RX PUBMED: 1423602.
RA Braun T., Rudnicki M. A., Arnold H. H., Jaenisch R.
RT Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death
RL Cell 71:369-382 (1992).
RN [5]; RE0003270.
RX PUBMED: 1741288.
RA Buonanno A., Apone L., Morasso M. I., Beers R., Brenner H. R., Eftimie R.
RT The MyoD family of myogenic factors is regulated by electrical activity: isolation and characterization of a mouse Myf-5 cDNA
RL Nucleic Acids Res. 20:539-544 (1992).
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