AC T01595
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ID T01595
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DT 28.11.1995 (created); ewi.
DT 17.01.2012 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA NF-YC
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SY CP1C (human); NF-YC (mouse).
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004112 Nfyc.
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HO HAP4 (yeast).
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CL C0075; heteromer-CCAAT; 4.2.1.0.3.1.
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SZ 334 AA; 37.2 kDa (cDNA) (calc.), 40 kDa (SDS)
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SQ MSTEGGFGSTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKM
SQ ISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPR
SQ DELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
SQ AQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQTQSGTGQTMQVMQQIITNTGEIQQIP
SQ VQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQLYQI
SQ QQVTMPAGQDLAQPMFIQSANQPSDGQTPQVTGD
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SC translated from EMBL #U17607
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FT 41 105 PF00808; Histone-like transcription factor (CBF/.
FT 45 108 predicted histone fold triple helix [3].
FT 45 108 PS50028; HIST_TAF.
FT 52 311 PF00478; IMP dehydrogenase / GMP reductase domai.
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SF N-terminal part is enriched in charged residues;
SF C-terminal 150 AA: enriched in hydrophobic and glutamine residues;
SF subunit of CP1/CBF [2];
SF subcomplex with CBF-A which is recognized by CBF-B [2];
SF CCAAT-binding complex with yeast HAP2/HAP3 [2];
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CP ubiquitous.
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FF no DNA-binding by its own [2];
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IN T00087 NF-YB; rat, Rattus norvegicus.
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MX M07302 V$NFY_Q3.
MX M00185 V$NFY_Q6.
MX M00775 V$NFY_Q6_01.
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BS R37753.
BS R37754.
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DR TRANSPATH: MO000025788.
DR EMBL: U17607;
DR UniProtKB: Q62725;
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RN [1]; RE0002858.
RX PUBMED: 1644837.
RA Maity S. N., Sinha S., Ruteshouser E. C., de Crombrugghe B.
RT Three different polypeptides are necessary for DNA binding of the mammalian heteromeric CCAAT binding factor
RL J. Biol. Chem. 267:16574-16580 (1992).
RN [2]; RE0003516.
RX PUBMED: 7878029.
RA Sinha S., Maity S. N., Lu J., de Crombrugghe B.
RT Recombinant rat CBF-C, the third subunit of CBF / NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3
RL Proc. Natl. Acad. Sci. USA 92:1624-1628 (1995).
RN [3]; RE0017971.
RX PUBMED: 9662544.
RA Edwards D., Murray J. A., Smith A. G.
RT Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis.
RL Plant Physiol. 117:1015-1022 (1998).
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