AC T01734
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ID T01734
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DT 12.03.1996 (created); ewi.
DT 15.04.2015 (updated); msr.
CO Copyright (C), QIAGEN.
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FA HOXB7
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SY Ghox-2.3 (chick); HHO.C1; homeo box B7; HOX2C.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009915 HOXB7; HGNC: HOXB7.
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HO Ubx (Drosophila).
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CL C0006; homeo; 3.1.1.6.5.
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SF binds to homeo domain binding sites in downstream homeobox genes with KD of 2-4 nM and with KD = 12 nM to that of an upstream gene [3];
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CP Expressed in melanocyte and all melanoma cell lines like A375, Me1559, Me10538, Me665/1, Me665/R, Me4405, Me1042/R, Me9742/2, Me3146, FM713, FM727 and NT2/D1 [4].
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MX M01396 V$HOXB7_01.
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BS R33711.
BS R22696.
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DR TRANSPATH: MO000025899.
DR UniProtKB: P09629;
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RN [1]; RE0003901.
RX PUBMED: 2573064.
RA Shen W. F., Largman C., Lowney P., Corral J. C., Detmer K., Hauser C. A., Simonitch T. A., Hack F. M., Lawrence H. J.
RT Lineage-restricted expression of homeobox-containing genes in human hematopoietic cell lines
RL Proc. Natl. Acad. Sci. USA 86:8536-8540 (1989).
RN [2]; RE0003963.
RX PUBMED: 2885844.
RA Simeone A., Mavilio F., Acampora D., Giampaolo A., Faiella A., Zappavigna V., D'Esposito M., Pannese M., Russo G., Boncinelli E., Peschle C.
RT Two human homeobox genes, c1 and c8: Structure analysis and expression in embryonic development
RL Proc. Natl. Acad. Sci. USA 84:4914-4918 (1987).
RN [3]; RE0003970.
RX PUBMED: 1357628.
RA Corsetti M. T., Briata P., Sanseverino L., Daga A., Airoldi I., Simeone A., Palmisano G., Angelini C., Boncinelli E., Corte G.
RT Differential DNA binding properties of three human homeodomain proteins
RL Nucleic Acids Res. 20:4465-4472 (1992).
RN [4]; RE0012439.
RX PUBMED: 8756643.
RA Care A., Silvani A., Meccia E., Mattia G., Stoppacciaro A., Parmiani G., Peschle C., Colombo M. P.
RT HOXB7 constitutively activates basic fibroblast growth factor in melanomas
RL Mol. Cell. Biol. 16:4842-4851 (1996).
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