TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01734 XX ID T01734 XX DT 12.03.1996 (created); ewi. DT 15.04.2015 (updated); msr. CO Copyright (C), QIAGEN. XX FA HOXB7 XX SY Ghox-2.3 (chick); HHO.C1; homeo box B7; HOX2C. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G009915 HOXB7; HGNC: HOXB7. XX HO Ubx (Drosophila). XX CL C0006; homeo; XX SF binds to homeo domain binding sites in downstream homeobox genes with KD of 2-4 nM and with KD = 12 nM to that of an upstream gene [3]; XX CP Expressed in melanocyte and all melanoma cell lines like A375, Me1559, Me10538, Me665/1, Me665/R, Me4405, Me1042/R, Me9742/2, Me3146, FM713, FM727 and NT2/D1 [4]. XX MX M01396 V$HOXB7_01. XX BS R33711. BS R22696. XX DR TRANSPATH: MO000025899. DR UniProtKB: P09629; XX RN [1]; RE0003901. RX PUBMED: 2573064. RA Shen W. F., Largman C., Lowney P., Corral J. C., Detmer K., Hauser C. A., Simonitch T. A., Hack F. M., Lawrence H. J. RT Lineage-restricted expression of homeobox-containing genes in human hematopoietic cell lines RL Proc. Natl. Acad. Sci. USA 86:8536-8540 (1989). RN [2]; RE0003963. RX PUBMED: 2885844. RA Simeone A., Mavilio F., Acampora D., Giampaolo A., Faiella A., Zappavigna V., D'Esposito M., Pannese M., Russo G., Boncinelli E., Peschle C. RT Two human homeobox genes, c1 and c8: Structure analysis and expression in embryonic development RL Proc. Natl. Acad. Sci. USA 84:4914-4918 (1987). RN [3]; RE0003970. RX PUBMED: 1357628. RA Corsetti M. T., Briata P., Sanseverino L., Daga A., Airoldi I., Simeone A., Palmisano G., Angelini C., Boncinelli E., Corte G. RT Differential DNA binding properties of three human homeodomain proteins RL Nucleic Acids Res. 20:4465-4472 (1992). RN [4]; RE0012439. RX PUBMED: 8756643. RA Care A., Silvani A., Meccia E., Mattia G., Stoppacciaro A., Parmiani G., Peschle C., Colombo M. P. RT HOXB7 constitutively activates basic fibroblast growth factor in melanomas RL Mol. Cell. Biol. 16:4842-4851 (1996). XX //