AC T01828
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ID T01828
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DT 20.05.1996 (created); ewi.
DT 03.08.2006 (updated); din.
CO Copyright (C), QIAGEN.
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FA Pax-8
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SY mPax-8; mPax8; PAX8.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006535 Pax8.
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CL C0017; paired; 3.2.2.2.3.
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SF Pax-8 contains a remnant of a homeo domain;
SF there may be many splice variants [1];
SF Kr of Pax-8 to the BS-I and BS-II site is 3.33 Exp 5 and 0.32 Exp 5 [3];
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FF Pax-2, Pax-5 and Pax-8 show overlapping expression with the engrailed genes and bind as activators to the En-2 5' enhancer [3];
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MX M00717 V$PAX8_01.
MX M00328 V$PAX8_B.
MX M00808 V$PAX_Q6.
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DR TRANSPATH: MO000025962.
DR UniProtKB: Q00288;
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RN [1]; RE0004297.
RX PUBMED: 8413205.
RA Kozmik Z., Kurzbauer R., Doerfler P., Busslinger M.
RT Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties
RL Mol. Cell. Biol. 13:6024-6035 (1993).
RN [2]; RE0004298.
RX PUBMED: 1723950.
RA Plachov D., Chowdhury K., Walther C., Simon D., Guenet J. L., Gruss P.
RT Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland
RL Development 110:643-651 (1990).
RN [3]; RE0014313.
RX PUBMED: 8625814.
RA Song D. L., Chalepakis G., Gruss P., Joyner A. L.
RT Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene
RL Development 122:627-635 (1996).
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