TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01828 XX ID T01828 XX DT 20.05.1996 (created); ewi. DT 03.08.2006 (updated); din. CO Copyright (C), QIAGEN. XX FA Pax-8 XX SY mPax-8; mPax8; PAX8. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G006535 Pax8. XX CL C0017; paired; XX SF Pax-8 contains a remnant of a homeo domain; SF there may be many splice variants [1]; SF Kr of Pax-8 to the BS-I and BS-II site is 3.33 Exp 5 and 0.32 Exp 5 [3]; XX FF Pax-2, Pax-5 and Pax-8 show overlapping expression with the engrailed genes and bind as activators to the En-2 5' enhancer [3]; XX MX M00717 V$PAX8_01. MX M00328 V$PAX8_B. MX M00808 V$PAX_Q6. XX DR TRANSPATH: MO000025962. DR UniProtKB: Q00288; XX RN [1]; RE0004297. RX PUBMED: 8413205. RA Kozmik Z., Kurzbauer R., Doerfler P., Busslinger M. RT Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties RL Mol. Cell. Biol. 13:6024-6035 (1993). RN [2]; RE0004298. RX PUBMED: 1723950. RA Plachov D., Chowdhury K., Walther C., Simon D., Guenet J. L., Gruss P. RT Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland RL Development 110:643-651 (1990). RN [3]; RE0014313. RX PUBMED: 8625814. RA Song D. L., Chalepakis G., Gruss P., Joyner A. L. RT Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene RL Development 122:627-635 (1996). XX //