AC T01870
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ID T01870
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DT 06.08.1996 (created); ewi.
DT 01.04.2003 (updated); cch.
CO Copyright (C), QIAGEN.
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FA POU2F2 (Oct-2.1)
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OS rat, Rattus rattus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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CL C0007; POU.
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SZ 463 AA; 49.4 kDa (cDNA) (calc.).
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SQ MVHSSMGAPEIRMSKPLEAEKQSLDSPSEHTDTERNGPDINHQNPQNKASPFSVSPTGPS
SQ TKIKAEDPSGDSAPAAPPPPQPAQPHLPQAQLMLTGSQLAGDIQQLLQLQQLVLVPGHHL
SQ QPPAQFLLPQAQQSQPGLLPTPNLFQLPQQTQGALLTSQPRAGLPTQPSKCLEPPSHPEE
SQ PSDLEELEQFARTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCK
SQ LKPLLEKWLNDAETMSVDSSLPSPNQLSSPSLGFDGLPGRRRKKRTSIETNVRFALEKSF
SQ LANQKPTSEEILLIAEQLHMEKEVIRVWFCNRRQKEKRINPCSAAPMLPSPGKPTSYSPH
SQ LVTPQGGAGTLPLSQASSSLSTTVTTLSSAVGTLHPSRTAGGGGGGGGAAPPLNSIPSVT
SQ PPPPATTNSTNPSPQGSHSAIGLTGLNPSAGPGLWWNPAPYQP
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SC translated from EMBL #L25863
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FT 179 253 PF00157; Pou domain - N-terminal to homeobox domain.
FT 179 253 SM00352; pou.
FT 279 339 PS50071; HOMEOBOX_2.
FT 279 341 PS50550; POU_HOMEODOMAIN.
FT 281 343 SM00389; HOX_1.
FT 282 338 PF00046; Homeobox domain.
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SF the four known splice variants (Oct-2.1, Oct-2/Oct2A/Oct-2.2, Oct-2.7, and Oct-2.8) differ in their DNA-binding specificity [3];
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IN T00643 POU2F1; rat, Rattus norvegicus.
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MX M01368 V$OCT2_01.
MX M03836 V$OCT2_Q6.
MX M00210 V$OCT_C.
MX M00795 V$OCT_Q6.
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BS R01176.
BS R03333.
BS R03334.
BS R03335.
BS R00841.
BS R00870.
BS R01884.
BS R03426.
BS R02226.
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DR TRANSPATH: MO000025992.
DR EMBL: L25863;
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RN [1]; RE0000423.
RX PUBMED: 2573523.
RA Schoeler H. R., Hatzopoulos A. K., Balling R., Suzuki N., Gruss P.
RT A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor
RL EMBO J. 8:2543-2550 (1989).
RN [2]; RE0002095.
RX PUBMED: 2011512.
RA Wirth T., Priess A., Annweiler A., Zwilling S., Oeler B.
RT Multiple Oct2 isoforms are generated by alternative splicing
RL Nucleic Acids Res. 19:43-51 (1991).
RN [3]; RE0004288.
RX PUBMED: 1281152.
RA Lillycrop K. A., Latchman D. S.
RT Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promoters
RL J. Biol. Chem. 267:24960-24965 (1992).
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