AC T01873
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ID T01873
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DT 08.08.1996 (created); ewi.
DT 18.06.2015 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA POU3F2
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SY Brain-2; Brn-2; Brn2; N-Oct-3; Oct-7; OTF7; POU domain, class 3, transcription factor 2; POU3F2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014511 Pou3f2.
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CL C0007; POU; 3.1.10.3.2.
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SF recognizes both octamer-containing sites and non-octamer sites [5];
SF binds as monomer and dimer where dimerization diminishes the transactivation ability [5];
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CP (E12:) brain [1]; (adult:) nervous system [3] [4] [3] [4] [1].
CN heart, kidney, liver, muscle, salivary gland, spleen, testis [4].
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MX M00145 V$BRN2_01.
MX M01477 V$OCTAMER_02.
MX M00795 V$OCT_Q6.
MX M00463 V$POU3F2_01.
MX M00464 V$POU3F2_02.
MX M07332 V$POU3F2_Q2.
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BS R29772.
BS R21516.
BS R04327.
BS R62432.
BS R68436.
BS R68441.
BS R68446.
BS R68447.
BS R01884.
BS R67204.
BS R23923.
BS R23924.
BS R25934.
BS R25935.
BS R67910.
BS R38152.
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DR TRANSPATH: MO000025994.
DR UniProtKB: P31360;
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RN [1]; RE0000423.
RX PUBMED: 2573523.
RA Schoeler H. R., Hatzopoulos A. K., Balling R., Suzuki N., Gruss P.
RT A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor
RL EMBO J. 8:2543-2550 (1989).
RN [2]; RE0002117.
RX PUBMED: 2216722.
RA Schreiber E., Harshman K., Kemler I., Malipiero U., Schaffner W., Fontana A.
RT Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins
RL Nucleic Acids Res. 18:5495-5503 (1990).
RN [3]; RE0004401.
RX PUBMED: 8441633.
RA Schreiber E., Tobler A., Malipiero U., Schaffner W., Fontana A.
RT cDNA cloning of human N-Oct 3, a nervous-system specific POU domain transcripton factor binding to the octamer DNA motif
RL Nucleic Acids Res. 21:253-258 (1993).
RN [4]; RE0004402.
RX PUBMED: 1565620.
RA Hara Y., Rovescalli A. C., Kim Y., Nirenberg M.
RT Structure and evolution of four POU domain genes expressed in mouse brain
RL Proc. Natl. Acad. Sci. USA 89:3280-3284 (1992).
RN [5]; RE0016787.
RX PUBMED: 9852081.
RA Rhee J. M., Gruber C. A., Brodie T. B., Trieu M., Turner E. E.
RT Highly cooperative homodimerization is a conserved property of neural POU proteins
RL J. Biol. Chem. 273:34196-34205 (1998).
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