TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01873 XX ID T01873 XX DT 08.08.1996 (created); ewi. DT 18.06.2015 (updated); jmh. CO Copyright (C), QIAGEN. XX FA POU3F2 XX SY Brain-2; Brn-2; Brn2; N-Oct-3; Oct-7; OTF7; POU domain, class 3, transcription factor 2; POU3F2. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G014511 Pou3f2. XX CL C0007; POU; XX SF recognizes both octamer-containing sites and non-octamer sites [5]; SF binds as monomer and dimer where dimerization diminishes the transactivation ability [5]; XX CP (E12:) brain [1]; (adult:) nervous system [3] [4] [3] [4] [1]. CN heart, kidney, liver, muscle, salivary gland, spleen, testis [4]. XX MX M00145 V$BRN2_01. MX M01477 V$OCTAMER_02. MX M00795 V$OCT_Q6. MX M00463 V$POU3F2_01. MX M00464 V$POU3F2_02. MX M07332 V$POU3F2_Q2. XX BS R29772. BS R21516. BS R04327. BS R62432. BS R68436. BS R68441. BS R68446. BS R68447. BS R01884. BS R67204. BS R23923. BS R23924. BS R25934. BS R25935. BS R67910. BS R38152. XX DR TRANSPATH: MO000025994. DR UniProtKB: P31360; XX RN [1]; RE0000423. RX PUBMED: 2573523. RA Schoeler H. R., Hatzopoulos A. K., Balling R., Suzuki N., Gruss P. RT A family of octamer-specific proteins present during mouse embryogenesis: evidence for germline-specific expression of an Oct factor RL EMBO J. 8:2543-2550 (1989). RN [2]; RE0002117. RX PUBMED: 2216722. RA Schreiber E., Harshman K., Kemler I., Malipiero U., Schaffner W., Fontana A. RT Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins RL Nucleic Acids Res. 18:5495-5503 (1990). RN [3]; RE0004401. RX PUBMED: 8441633. RA Schreiber E., Tobler A., Malipiero U., Schaffner W., Fontana A. RT cDNA cloning of human N-Oct 3, a nervous-system specific POU domain transcripton factor binding to the octamer DNA motif RL Nucleic Acids Res. 21:253-258 (1993). RN [4]; RE0004402. RX PUBMED: 1565620. RA Hara Y., Rovescalli A. C., Kim Y., Nirenberg M. RT Structure and evolution of four POU domain genes expressed in mouse brain RL Proc. Natl. Acad. Sci. USA 89:3280-3284 (1992). RN [5]; RE0016787. RX PUBMED: 9852081. RA Rhee J. M., Gruber C. A., Brodie T. B., Trieu M., Turner E. E. RT Highly cooperative homodimerization is a conserved property of neural POU proteins RL J. Biol. Chem. 273:34196-34205 (1998). XX //