AC T01878
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ID T01878
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DT 08.08.1996 (created); ewi.
DT 30.03.2009 (updated); ach.
CO Copyright (C), QIAGEN.
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FA POU4F1
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SY Brn-3.0; Brn-3a; Brn-3a(s); Brn3a.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002463 Pou4f1.
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CL C0007; POU.
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SZ 337 AA; 33.6 kDa (cDNA) (calc.).
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SQ MNSVPCTSTSTVPLAHHHHHHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAGGGGGAH
SQ DGPGGGGGPGGGGGPGGGGPGGGGGGGGPGGGGGAPGGGLLGGSAHPHPHMHGLGHLSHP
SQ AAAAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGAAGLASICDSD
SQ TDPRELEAFAERFKQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFESLTLSHNNM
SQ IALKPILQAWLEEAEGAQREKMNKPELFNGGEKKRKRTSIAAPEKRSLEAYFAVQPRPSS
SQ EKIAAIAEKLDLKKNVVRVWFCNQRQKQKRMKFSATY
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SC translated from EMBL #S69350 and edited
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FT 178 255 PF00157; Pou domain - N-terminal to homeobox domain.
FT 178 255 SM00352; pou.
FT 271 331 PS50071; HOMEOBOX_2.
FT 271 333 PS50550; POU_HOMEODOMAIN.
FT 273 335 SM00389; HOX_1.
FT 274 330 PF00046; Homeobox domain.
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SF a longer variant is POU4F1(l) which may arise from alternative translation initiation codon usage [1];
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FF in contrast to POU4F1(l), POU4F1(s) has no transforming potential [1];
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MX M00795 V$OCT_Q6.
MX M07060 V$POU4F1_Q3.
MX M03843 V$POU4F1_Q6.
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DR TRANSPATH: MO000025998.
DR UniProtKB: P17208;
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RN [1]; RE0004385.
RX PUBMED: 8290353.
RA Theil T., McLean-Hunter S., Zoernig M., Moeroey T.
RT Mouse BRN-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of BRN-3A
RL Nucleic Acids Res. 21:5921-5929 (1993).
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