AC T02005
XX
ID T02005
XX
DT 16.12.1996 (created); ewi.
DT 21.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA Dll
XX
SY Brista; Distal-less.
XX
OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
XX
GE G018888 Dll.
XX
HO Dlx-1, Dlx-2, Dlx-3 (mouse).
XX
CL C0006; homeo.
XX
SZ 327 AA; 35.2 kDa (cDNA) (calc.).
XX
SQ MDAPDAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGG
SQ QDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVNGK
SQ GKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYK
SQ KMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGGNNGGGSNSGSPSHYLPPGHSPTPS
SQ STPVSELSPEFPPTGLSPPTQAPWDQKPHWIDHKPPPQMTPQPPHPAATLHPQTHHHNPP
SQ PQMGGYVPQYWYLPETNPSLVTVWPAV
XX
SC translated from EMBL #L02539
XX
FT 122 182 
PS50071; HOMEOBOX_2.
FT 124 186 
SM00389; HOX_1.
FT 125 181 
PF00046; Homeobox domain.
XX
FF required for development of larval and adult limbs to specify the pattern along the proximal-distal axis [2];
FF expression is repressed in the abdomen by genes of the BX-C complex [1];
FF distinct sites in the dll enhancer govern expression in larval leg primordia and repression by BX-C proteins [1];
XX
MX M02305 I$DLL_01.
MX M07784 I$DLL_02.
XX
DR TRANSPATH: MO000026085.
DR EMBL: L02539;
DR UniProtKB: P20009;
DR FLYBASE: FBgn0000157; Dll.
XX
RN [1]; RE0004952.
RX PUBMED: 1358457.
RA Vachon G., Cohen B., Pfeifle C., McGuffin M. E., Botas J., Cohen S. M.
RT Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less
RL Cell 71:437-450 (1992).
RN [2]; RE0005084.
RX PUBMED: 2564639.
RA Cohen S. M., Broenner G., Kuettner F., Juergens G., Jaeckle H.
RT Distal-less encodes a domain protein required for limb development in Drosophila
RL Nature 338:432-434 (1989).
XX
//