AC T02078
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ID T02078
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DT 29.01.1997 (created); ewi.
DT 27.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Otd
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SY Oc; Ocelliless; Orthodenticle.
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OS fruit fly, Drosophila melanogaster
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
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GE G041675 oc.
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HO Otx1 (mammalia).
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CL C0006; homeo.
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SZ 671 AA; 69.7 kDa (gene) (calc.).
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SQ MAAGFLKSGDLGPHPHSYGGPHPHHSVPHGPLPPGMPMPSLGPFGLPHGLEAVGFSQGMW
SQ GDLCYPGVNTRKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVW
SQ FKNRRAKCRQQLQQQQQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNNTQS
SQ SGGNNSNKSSQKQGNSQSSQQGGGSSGGNNSNNNSAAAAASAAAAVAAAQSIKTHHSSFL
SQ SAAAAASAQSIKTHHSSFLSAAAAASGGTNQSANNNSNNNNQGNSTPNSSSSGGGSQAGG
SQ HLSAAAAAAALNVTAAHQNSSPLLPTPATSVSPVSIVCKKEHLSGGYGSSVGGGGGGGGG
SQ GASSGGLNLGVGVGVGVGVGVGVSQDLLRSPYDQLKDAGGDIGAGVHHHHSIYGSAAGSN
SQ PRLLQPGGNITPMDSSSSITTPSPPITPMSPQSAPQRPMPPNRPSPPTILPPIRPPICPI
SQ MIRITSGTISTSNIRITMPRRPATTHRWSTLAIRIRSTTTWAIRATRPPILVCRHRHPSR
SQ APCPRRPSPRTAWITCRRRISTRIWCRIYSSNTAAVAATTTVQRGQVVRVRVRVRVRVLV
SQ LVVDLVLVLVLVLDRGAIVLPSWSSTIISSTSTSYSSISITRIITRINTRITTAIIIISS
SQ NTIMMMNSDRI
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SC Swiss-Prot#P22810
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FT 61 430 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 71 131 
PS50071; HOMEOBOX_2.
FT 73 129 
PS50552; PAX.
FT 73 135 
SM00389; HOX_1.
FT 74 130 
PF00046; Homeobox domain.
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SF homeo domain is most related to that of the Paired class [1];
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FF required for normal development of the central nervous system (CNS), in particular for the neuropil, for some neurons associated with the midline of the CNS and for the ocelli [1];
FF expression in a stripe near the anterior pole of the cellular blastoderm;
FF later found in the CNS in regions where specific neurons arise from [1];
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MX M02352 I$OC_01.
MX M07811 I$OC_02.
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DR TRANSPATH: MO000026144.
DR EMBL: X58983;
DR UniProtKB: P22810;
DR FLYBASE: FBgn0004102; oc.
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RN [1]; RE0005170.
RX PUBMED: 1979296.
RA Finkelstein R., Smouse D., Capaci T. M., Spradling A. C., Perrimon N.
RT The orthodenticle gene encodes a novel homeo domain protein involved in the development of the Drosophila nervous system and ocellar visual structures
RL Genes Dev. 4:1516-1527 (1990).
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//