AC T02220
XX
ID T02220
XX
DT 22.10.1997 (created); ili.
DT 15.02.2005 (updated); cch.
CO Copyright (C), QIAGEN.
XX
FA AML1DeltaN
XX
SY AML1; CBF-alpha 2; CBFA2; PEBP2alphaB; RUNX1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G003993 RUNX1; HGNC: RUNX1.
XX
CL C0029; runt; 6.4.1.0.2.11.
XX
SZ 348 AA; 37.7 kDa (cDNA) (calc.), 43 kDa (SDS) [1]
XX
SQ MAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRA
SQ IKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRAS
SQ LNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTT
SQ LSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMG
SQ SATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPC
SQ TNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
XX
SC translated from EMBL #D89788
XX
FT 1 73 
PS51062; RUNT.
FT 1 77 
PF00853; Runt domain.
XX
SF does not bind to DNA, does not bind to the beta subunit protein [1];
SF alternatively spliced isoform of AML1;
XX
CP hematopoietic cell lines from lymphoid to myeloid origin [1].
XX
FF modulator of AML1 function [1];
FF coprecipitates with Ets-1 [1];
XX
MX M00271 V$AML1_01.
MX M01658 V$AML1_Q4.
MX M07242 V$AML1_Q4_01.
MX M08865 V$AML1_Q4_02.
MX M08866 V$AML_Q4.
MX M00769 V$AML_Q6.
MX M00984 V$PEBP_Q6.
XX
DR TRANSPATH: MO000026235.
DR EMBL: D89788;
DR UniProtKB: Q01196-11;
XX
RN [1]; RE0005911.
RX PUBMED: 9199349.
RA Zhang Y., Bae S., Huang G., Fu Y., Lu J., Ahn M., Kanno Y., Kanno T., Ito Y.
RT A novel transcript encoding an N-terminally truncated AML1 / PEBP2alphaB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells
RL Mol. Cell. Biol. 17:4133-4145 (1997).
XX
//