AC T02350
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ID T02350
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DT 20.02.1998 (created); tme.
DT 18.12.2008 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA BF-1
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SY BF-1; FKHL1; FOXG1B; HFK1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G006093 FOXG1; HGNC: Foxg1.
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HO FKH (Drosophila).
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CL C0023; fork head; 3.3.1.7.1.
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SF belongs to the FHK/HNF3 family;
SF VP motif is conserved between FOXG1B and Pax-9 factors and is located C-terminal to the DNA binding domain [2];
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CP fetal brain [1].
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FF repressor [2];
FF product of the c-qin proto-oncogene;
FF regulator of developing brain;
FF directly interacts with PLU-1, which results in a more pronounced transcriptional repression [2];
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MX M04243 V$FOXG1_02.
MX M07989 V$FOXG1_06.
MX M01216 V$FOXO1_Q5.
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DR TRANSPATH: MO000026342.
DR UniProtKB: P55316;
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RN [1]; RE0006385.
RX PUBMED: 7959731.
RA Murphy D. B., Wiese S., Burfeind P., Schmundt D., Mattei M. G., Schulz-Schaeffer W., Thies U.
RT Human brain factor 1, a new member of the fork head gene family
RL Genomics 21:551-557 (1994).
RN [2]; RE0023712.
RX PUBMED: 12657635.
RA Tan K., Shaw A. L., Madsen B., Jensen K., Taylor-Papadimitriou J., Freemont P. S.
RT Human PLU-1 Has transcriptional repression properties and interacts with the developmental transcription factors BF-1 and PAX9.
RL J. Biol. Chem. 278:20507-20513 (2003).
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