AC T02515
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ID T02515
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DT 10.08.1998 (created); tme.
DT 23.09.2015 (updated); hna.
CO Copyright (C), QIAGEN.
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FA foxm1
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SY FKH16; Trident.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006101 Foxm1.
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CL C0023; fork head; 3.3.1.13.1.
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CP (embryonic) E14 heart, brain, liver, lung, kidney, limbs [2], d16 p.c. proliferating epithelial and mesenchymal cells of lung, liver, intestine, and renal cortex, urinary tract [4]; (adult) intestinal crypts, testis, thymus, colon [4] [2] [4].
CN (adult) kidney, liver (hepatocytes, but reactivatable), spleen, heart, lung, brain, muscle, gut.
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FF is required to maintain pancreatic beta-cell mass [5];
FF expression is increased with the beginning of the S-phase;
FF shows transactivating capability [2];
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MX M00630 V$FOXM1_01.
MX M04663 V$FOXM1_03.
MX M04664 V$FOXM1_04.
MX M04611 V$FOXM1_Q3.
MX M08883 V$FOXM1_Q3_02.
MX M07255 V$FOXM1_Q6.
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BS R69780.
BS R66345.
BS R65061.
BS R67529.
BS R67532.
BS R67533.
BS R73167.
BS R73169.
BS R68049.
BS R68052.
BS R68050.
BS R68051.
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DR TRANSPATH: MO000026495.
DR UniProtKB: O08696;
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RN [1]; RE0006655.
RA TRANSFAC_Team.
RT Revisions of transcription factor domains
RL TRANSFAC Reports 1:0002 (1998).
RN [2]; RE0006961.
RX PUBMED: 9108152.
RA Korver W., Roose J., Clevers H.
RT The winged-helix transcriptions factor Trident is expressed in cycling cells
RL Nucleic Acids Res. 25:1715-1719 (1997).
RN [3]; RE0006962.
RX PUBMED: 9441747.
RA Korver W., Roose J., Heinen K., Weghuis D. O., de Bruijn D., van Kessel A. G., Clevers H.
RT The human TRIDENT/HFH-11/FKHL12 gene: structure, localization and promoter characterization
RL Genomics 46:435-442 (1997).
RN [4]; RE0006963.
RX PUBMED: 9032290.
RA Ye H., Kelly T. F., Samadani U., Lim L., Rubio S., Overdier D. G., Roebuck K. A., Costa R. H.
RT Hepatocyte Nuclear Factor 3/ fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues
RL Mol. Cell. Biol. 17:1626-1641 (1997).
RN [5]; RE0048397.
RX PUBMED: 16556734.
RA Zhang H., Ackermann A. M., Gusarova G. A., Lowe D., Feng X., Kopsombut U. G., Costa R. H., Gannon M.
RT The FoxM1 transcription factor is required to maintain pancreatic beta-cell mass.
RL Mol. Endocrinol. 20:1853-1866 (2006).
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