AC T02896
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ID T02896
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DT 13.01.2000 (created); sur.
DT 11.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Sox-15
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SY Sox-15; Sox15.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002879 Sox15.
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HO SOX20 (human).
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CL C0015; HMG; 4.1.1.7.1.
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SF member of the murine Sox family;
SF most closely related to the subgroup which includes Sox 1-3 and Sox 14 [1];
SF first cloning of HMG domain of SOX-15 [1];
SF 2 aa conflict in EMBL AB014474: position 71 is E (instead of K) and position 97 is V (instead of M);
SF 74% amino acid identity with the human SOX20 T04855 [3];
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CP highly expressed in undifferentiated MG1.19 and RF8 ES cells, weak expression in stomach and skin [4].
CN T cells [1]; not expressed in differentiated cells (COS7 cells) [4].
EX brain,,,adult; high; RT-PCR; mRNA (poly-A); [3].
EX brain,,,adult; none; Northern blot; mRNA (poly-A); [3].
EX diaphragm,,,adult; low; RT-PCR; mRNA (poly-A); [3].
EX diaphragm,,,adult; none; Northern blot; mRNA (poly-A); [3].
EX heart,,,adult; low; RT-PCR; mRNA (poly-A); [3].
EX heart,,,adult; none; Northern blot; mRNA (poly-A); [3].
EX intestine,,,adult; low; RT-PCR; mRNA (poly-A); [3].
EX intestine,,,adult; none; Northern blot; mRNA (poly-A); [3].
EX kidney (right and left),,,adult; low; RT-PCR; mRNA (poly-A); [3].
EX kidney (right and left),,,adult; none; Northern blot; mRNA (poly-A); [3].
EX liver,,,adult; low; RT-PCR; mRNA (poly-A); [3].
EX liver,,,adult; none; Northern blot; mRNA (poly-A); [3].
EX mouse, Mus musculus,,,Theiler Stage 13; low; RT-PCR; mRNA (poly-A); [3].
EX mouse, Mus musculus,,,Theiler Stage 13; none; Northern blot; mRNA (poly-A); [3].
EX mouse, Mus musculus,,,Theiler Stage 15; high; RT-PCR; mRNA (poly-A); [3].
EX mouse, Mus musculus,,,Theiler Stage 15; none; Northern blot; mRNA (poly-A); [3].
EX muscles,,,adult; high; RT-PCR; mRNA (poly-A); [3].
EX muscles,,,adult; none; Northern blot; mRNA (poly-A); [3].
EX testis (right and left),,,adult; low; RT-PCR; mRNA (poly-A); [3].
EX testis (right and left),,,adult; none; Northern blot; mRNA (poly-A); [3].
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FF acts as negative regulator of myoblast differentiation [3];
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IN T09363 Oct3; mouse, Mus musculus.
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MX M02799 V$SOX15_03.
MX M02903 V$SOX15_04.
MX M03847 V$SOX15_Q3.
MX M08899 V$SOX_Q4.
MX M01014 V$SOX_Q6.
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BS R22359.
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DR TRANSPATH: MO000026864.
DR UniProtKB: P43267;
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RN [1]; RE0013990.
RX PUBMED: 8479922.
RA van de Wetering M., Clevers H.
RT Sox 15, a novel member of the murine Sox family of HMG box transcription factors
RL Nucleic Acids Res. 21:1669-1669 (1993).
RN [2]; RE0014423.
RX PUBMED: 10524236.
RA Miyashita A., Shimizu N., Endo N., Hanyuu T., Ishii N., Ito K., Itoh Y., Shirai M., Nakajima T., Odani S., Kuwano R.
RT Five different genes, Eif4a1, Cd68, Supl15h, Sox15 and Fxr2h, are clustered in a 40 kb region of mouse chromosome 11
RL Gene 237:53-60 (1999).
RN [3]; RE0017069.
RX PUBMED: 10821863.
RA Beranger F., Mejean C., Moniot B., Berta P., Vandromme M.
RT Muscle differentiation is antagonized by SOX15, a new member of the SOX protein family
RL J. Biol. Chem. 275:16103-16109 (2000).
RN [4]; RE0050892.
RX PUBMED: 15863505.
RA Maruyama M., Ichisaka T., Nakagawa M., Yamanaka S.
RT Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells.
RL J. Biol. Chem. 280:24371-24379 (2005).
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