AC T03239
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ID T03239
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DT 11.04.2000 (created); sth.
DT 10.01.2014 (updated); vad.
CO Copyright (C), QIAGEN.
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FA DDB-2
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SY Damage-specific DNA-binding protein 2; DDB p48 subunit; DDBb; DNA damage-binding protein 2; UV-damaged DNA-binding protein 2; UV-DDB 2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005981 DDB2; HGNC: DDB2.
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SF Human damage-specific DNA binding protein p48 subunit [1];
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CP tissue-epidermal, epithelial [1].
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IN T34283 histone H2A{ub}; human, Homo sapiens.
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BS R59628.
BS R59629.
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DR TRANSPATH: MO000027185.
DR UniProtKB: Q92466;
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RN [1]; RE0014385.
RX PUBMED: 8530102.
RA Dualan R., Brody T., Keeney S., Nichols A. F., Admon A., Linn S.
RT Chromosomal localization and cDNA cloning of the genes (DDB1 and DDB2) for the p127 and p48 subunits of a human damage-specific DNA binding protein
RL Genomics 29:62-69 (1995).
RN [2]; RE0048810.
RX PUBMED: 17000644.
RA Vertegaal A. C., Andersen J. S., Ogg S. C., Hay R. T., Mann M., Lamond A. I.
RT Distinct and overlapping sets of SUMO-1 and SUMO-2 target proteins revealed by quantitative proteomics.
RL Mol. Cell. Proteomics 5:2298-2310 (2006).
RN [3]; RE0063245.
RX PUBMED: 16473935.
RA Kapetanaki M. G., Guerrero-Santoro J., Bisi D. C., Hsieh C. L., Rapic-Otrin V., Levine A. S.
RT The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites.
RL Proc. Natl. Acad. Sci. USA 103:2588-2593 (2006).
RN [4]; RE0071730.
RX PUBMED: 20178741.
RA Li W., You L., Cooper J., Schiavon G., Pepe-Caprio A., Zhou L., Ishii R., Giovannini M., Hanemann C. O., Long S. B., Erdjument-Bromage H., Zhou P., Tempst P., Giancotti F. G.
RT Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus.
RL Cell 140:477-490 (2010).
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