AC T03267
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ID T03267
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DT 02.05.2000 (created); rio.
DT 20.11.2007 (updated); sba.
CO Copyright (C), QIAGEN.
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FA Six-2
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G014337 SIX2; HGNC: SIX2.
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HO sine oculis (Drosophila).
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CL C0006; homeo; 3.1.6.1.2.
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SF in contrast to mouse Six-2 is expressed in human fetal eye [1];
SF Six proteins can be subdivided into three major families on the basis of sequence conservation in their homeo domain and six domain (Six-1/2/11, Six-3/6/7/10, Six-4/5/8) [2];
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EX brain,,,adult; none; Northern blot; RNA (undefined); [1].
EX brain,,,fetal; detectable; RT-PCR; total RNA; [1].
EX breast,,,fetal; none; RT-PCR; total RNA; [1].
EX eye and related structures (right and left),,,fetal; detectable; RT-PCR; total RNA; [1].
EX heart,,,adult; none; RT-PCR; total RNA; [1].
EX heart,,,adult; very low; Northern blot; RNA (undefined); [1].
EX heart,,,fetal; detectable; RT-PCR; total RNA; [1].
EX kidney (right and left),,,adult; none; Northern blot; RNA (undefined); [1].
EX kidney (right and left),,,adult; none; RT-PCR; total RNA; [1].
EX kidney (right and left),,,fetal; detectable; RT-PCR; total RNA; [1].
EX liver,,,adult; none; Northern blot; RNA (undefined); [1].
EX liver,,,adult; none; RT-PCR; total RNA; [1].
EX liver,,,fetal; detectable; RT-PCR; total RNA; [1].
EX lung (right and left),,,adult; none; Northern blot; RNA (undefined); [1].
EX lung (right and left),,,adult; none; RT-PCR; total RNA; [1].
EX lung (right and left),,,fetal; none; RT-PCR; total RNA; [1].
EX middle ear,,,fetal; detectable; RT-PCR; total RNA; [1].
EX muscles,,,adult; detectable; RT-PCR; total RNA; [1].
EX muscles,,,adult; none; Northern blot; RNA (undefined); [3].
EX muscles,,,adult; very high; Northern blot; RNA (undefined); [1].
EX muscles,,,fetal; detectable; RT-PCR; total RNA; [1].
EX optic nerve,,,adult; none; RT-PCR; total RNA; [1].
EX ovary (right and left),,,adult; detectable; RT-PCR; total RNA; [1].
EX pancreas,,,adult; detectable; RT-PCR; total RNA; [1].
EX pancreas,,,adult; low; Northern blot; RNA (undefined); [1].
EX placenta,,,adult; none; Northern blot; RNA (undefined); [1].
EX retina,,,adult; none; RT-PCR; total RNA; [1].
EX sclera,,,adult; detectable; RT-PCR; total RNA; [1].
EX skeleton of lower limb (right and left),,,fetal; detectable; RT-PCR; total RNA; [1].
EX skeleton of upper limb (right and left),,,fetal; detectable; RT-PCR; total RNA; [1].
EX small intestine,,,fetal; detectable; RT-PCR; total RNA; [1].
EX vertebral column,,,fetal; detectable; RT-PCR; total RNA; [1].
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MX M01433 V$SIX2_01.
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DR TRANSPATH: MO000027205.
DR UniProtKB: Q9NPC8; SIX2_HUMAN.
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RN [1]; RE0014441.
RX PUBMED: 10773454.
RA Boucher C. A., Winchester C. L., Hamilton G. M., Winter A. D., Johnson K. J., Bailey M. E.
RT Structure, mapping and expression of the human gene encoding the homeodomain protein, SIX2
RL Gene 247:145-151 (2000).
RN [2]; RE0014529.
RX PUBMED: 10381573.
RA Seo H. C., Curtiss J., Mlodzik M., Fjose A.
RT Six class homeobox genes in drosophila belong to three distinct families and are involved in head development
RL Mech. Dev. 83:127-139 (1999).
RN [3]; RE0014473.
RX PUBMED: 8617500.
RA Boucher C. A., Carey N., Edwards Y. H., Siciliano M. J., Johnson K. J.
RT Cloning of the human SIX1 gene and its assignment to chromosome 14
RL Genomics 33:140-142 (1996).
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