AC T03269
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ID T03269
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DT 02.05.2000 (created); sth.
DT 18.07.2008 (updated); tgo.
CO Copyright (C), QIAGEN.
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FA Rox
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SY MNT (Max binding protein).
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006427 Mnt.
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CL C0012; bHLH-ZIP; 1.2.6.7.6.
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SF nuclear location;
SF efficient DNA binding requires dimerization with another BHLH protein;
SF binds DNA as an homodimer or a heterodimer with Max;
SF binds to the canonical E box sequence 5'-CACGTG-3' and with higher affinity to 5'-CACGCG-3' [2];
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FF transcriptional regulator;
FF repressor [2];
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DR TRANSPATH: MO000027207.
DR UniProtKB: O08789;
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RN [1]; RE0013521.
RX PUBMED: 9000049.
RA Hurlin P. J., Queva C., Eisenmann R. N.
RT Mnt, a novel Max-interacting protein is coexpressed with Myc in proliferating cells and mediates repression at Myc binding sites.
RL Genes Dev. 11:44-58 (1997).
RN [2]; RE0014442.
RX PUBMED: 9184233.
RA Meroni G., Reymond A., Alcalay M., Borsani G., Tanigami A., Tonlorenzi R., Nigro C. L., Messali S., Zollo M., Ledbetter D. H., Brent R., Ballabio A., Carrozzo R.
RT Rox, a novel bHLHZip protein expressed in quiescent cells that heterodimerizes with Max, binds a non-canonical E box and acts as a transcriptional repressor
RL EMBO J. 16:2892-2906 (1997).
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