AC T03406
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ID T03406
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DT 31.05.2000 (created); rio.
DT 03.03.2015 (updated); pro.
CO Copyright (C), QIAGEN.
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FA MRG2
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SY Meis3; Mrg-2; Mrg2; myeloid ecotropic viral integration site 3.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006436 Meis3.
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HO Pbx (vertebrates), Exd (Drosophila).
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CL C0006; homeo; 3.1.4.2.3.
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SF TALE (three amino acid loop extension) homeo domain superclass [1];
SF high homology to Meis-1 over the entire sequence (69.9% amino acid identity) [2];
SF Meis-2 and MRG2 are probably not targets for retroviral integration in BHX-2 myeloid leukemias in contrast to Meis-1 [2];
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CP (adult:) heart, brain, spleen, lung [2].
CN (embryo:) not expressed until 11 days, (adult:) liver skeletal muscle, kidney [2].
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MX M04034 V$MEIS3_04.
MX M01395 V$MRG2_01.
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DR TRANSPATH: MO000027342.
DR UniProtKB: P97368;
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RN [1]; RE0014544.
RX PUBMED: 9336443.
RA Burglin T. R.
RT Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals
RL Nucleic Acids Res. 25:4173-4180 (1997).
RN [2]; RE0014560.
RX PUBMED: 8950991.
RA Nakamura T., Jenkins N. A., Copeland N. G.
RT Identification of a new family of Pbx-related homeobox genes
RL Oncogene 13:2235-2242 (1996).
RN [3]; RE0014564.
RX PUBMED: 10096059.
RA Salzberg A., Elias S., Nachaliel N., Bonstein L., Henig C., Frank D.
RT A Meis family protein caudalizes neural cell fates in Xenopus
RL Mech. Dev. 80:3-13 (1999).
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