
AC T03526
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ID T03526
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DT 03.07.2000 (created); sth.
DT 16.12.2014 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA E2F-2
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SY E130207A07; E2F transcription factor 2; E2f2.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002970 E2f2.
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CL C0023; fork head; 3.3.2.1.2.
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SF prior to crystal structure belongs to bHLH-zip factors [2];
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FF transcriptional regulator, activator [1];
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MX M02742 V$E2F2_03.
MX M02846 V$E2F2_04.
MX M00050 V$E2F_02.
MX M08875 V$E2F_Q4_03.
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BS R65296.
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DR TRANSPATH: MO000027461.
DR UniProtKB: P56931;
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RN [1]; RE0014062.
RX PUBMED: 9376316.
RA Dagnino L., Fry C. J., Bartley S. M., Farnham P., Gallie B. L., Phillips R. A.
RT Expression patterns of the E2F family of transcription factors during mouse nervous system development
RL Mech. Dev. 66:13-25 (1997).
RN [2]; RE0015322.
RX PUBMED: 10090723.
RA Zheng N., Fraenkel E., Pabo C. O., Pavletich N. P.
RT Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP
RL Genes Dev. 13:666-674 (1999).
RN [3]; RE0065683.
RX PUBMED: 20016601.
RA Chen D., Pacal M., Wenzel P., Knoepfler P. S., Leone G., Bremner R.
RT Division and apoptosis of E2f-deficient retinal progenitors.
RL Nature 462:925-929 (2009).
RN [4]; RE0065991.
RX PUBMED: 20016602.
RA Chong J. L., Wenzel P. L., Saenz-Robles M. T., Nair V., Ferrey A., Hagan J. P., Gomez Y. M., Sharma N., Chen H. Z., Ouseph M., Wang S. H., Trikha P., Culp B., Mezache L., Winton D. J., Sansom O. J., Chen D., Bremner R., Cantalupo P. G., Robinson M. L., Pipas J. M., Leone G.
RT E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
RL Nature 462:930-934 (2009).
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