AC T03732
XX
ID T03732
XX
DT 29.08.2000 (created); rio.
CO Copyright (C), QIAGEN.
XX
FA Om(1D)
XX
SY Bar homeobox 1; BarH1; optic morphology mutation ID.
XX
OS fruit fly, Drosophila ananassae
OC Eukaryota; Metazoa; Arthropoda; Tracheata; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila
XX
HO BarH1 T03926 (D. melanogaster).
XX
CL C0006; homeo.
XX
SZ 606 AA; 61.7 kDa (calc.).
XX
SQ MKDSMSILTQTPSETPAAHSQLHHHLSHHHHPALHHHPVLQHHYSLQQQHQQQQQQQPPA
SQ PPAVATTTVVNMSGSTTTAANLKPNRSRFMINDILAGSAAAAFYKQQQQHHHHHHQSHHN
SQ NNNHSGGSSGGTSPTHHNNNNGEGFEPPSGGAGAGAGAAAPPPPLHHLHPQSHPHPHPHP
SQ HSHPHPHALVHPHAKLAAGGGAANGLNVAQYAAAMQQHYAAAAAAAAARNSAAAAAAAAA
SQ AAASAAAAGGGGGGGLGVGGAPAGAELDDSSDYHEENEDCDSDEGGSAGGGGGGSNHMDD
SQ HSVCSNGGKDDDGNSIKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQE
SQ RQELAHKLDLSDCQVKTWYQNRRTKWMRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWP
SQ YAAAAGAGAAAAAAHGATPHTSIDIYYRQAAAAAAMQKPLPYNLYAGVPNVGVGVGVGVG
SQ PAPFSHLSASSSLSSLSSYYQSAAAAAAAANPGGPPPPPPPSSAAAATGGSPSPIGGLIK
SQ PLAGSPTGGMPPHHPSRPDSASPPLPLPLARPPSTPSPTLNPGSPPGRSVDSCSQAQSDD
SQ EDQIQV
XX
SC translated from EMBL #X56682
XX
FT 24 399 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 329 389 
PS50071; HOMEOBOX_2.
FT 331 393 
SM00389; HOX_1.
FT 332 388 
PF00046; Homeobox domain.
XX
SF 82% amino acid homology to BarH1 T03926 of Drosophila melanogaster [2];
XX
FF Om(D) and also Bar(B) T03926 mutation result in suppression of ommatidium differentiation at the anterior portion of the eye due to transient overexpression of BarH1 in the late third-instar larvae [2];
XX
DR TRANSPATH: MO000027662.
DR EMBL: X56682;
DR UniProtKB: P22544;
XX
RN [1]; RE0015020.
RX PUBMED: 1671353.
RA Tanda S., Corces V. G.
RT Retrotransposon-induced overexpression of a homeobox gene causes defects in eye morphogenesis in Drosophila
RL EMBO J. 10:407-417 (1991).
RN [2]; RE0015169.
RX PUBMED: 1674606.
RA Kojima T., Ishimaru S., Higashijima S., Takayama E., Akimaru H., Sone M., Emori Y., Saigo K.
RT Identification of a different-type homeobox gene, BarH1, possibly causing Bar (B) and Om(1D) mutations in Drosophila
RL Proc. Natl. Acad. Sci. USA 88:4343-4347 (1991).
XX
//