AC T04054
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ID T04054
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DT 01.12.2000 (created); rio.
DT 20.11.2007 (updated); man.
CO Copyright (C), QIAGEN.
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FA Meox2
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SY Gax; growth arrest-specific homeobox; mesenchyme homeobox factor 2; Mox-2; MOX2.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002122 Meox2.
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CL C0006; homeo; 3.1.1.14.2.
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SF 99% amino acid identity to murine Meox2 T04048 [1];
SF rapidly and transiently down-regulated in vascular smooth muscle cells during transition from G0 to G1 induced by mitogen (platelet-derived growth factor, fetal calf serum) stimulation [2];
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CP (embryo:) cardiovascular system, mesodermal tissues, some ectodermal tissues, (adult:) aorta, heart, kidney, lung, (cell lines:) ASM (aorta smooth muscle cells), Me (mesangial cells) [2].
CN (adult:) brain, liver, skeletal muscle, spleen, stomach, testes, intestine, pancreas, (cell lines:) A7r5, A10, NIH 3T3, C2C12human foreskin fibroblasts [2].
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FF probably growth repression function [2];
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DR TRANSPATH: MO000027963.
DR UniProtKB: P39020;
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RN [1]; RE0015400.
RX PUBMED: 7909944.
RA Candia A. F., Kovalik J. P., Wright C. V.
RT Amino acid sequence of Mox-2 and comparison to its Xenopus and rat homologs
RL Nucleic Acids Res. 21:4982-4982 (1993).
RN [2]; RE0015422.
RX PUBMED: 8098844.
RA Gorski D. H., LePage D. F., Patel C. V., Copeland N. G., Jenkins N. A., Walsh K.
RT Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells
RL Mol. Cell. Biol. 13:3722-3733 (1993).
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