AC T04169
XX
ID T04169
XX
DT 10.01.2001 (created); rio.
DT 20.08.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
XX
FA FOXJ2-long
XX
SY FHX.L; fork head homologous X, long isoform.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G009553 FOXJ2; HGNC: Foxj2.
XX
CL C0023; fork head; 3.3.1.10.2.1.
XX
SZ 574 AA; 62.4 kDa (cDNA) (calc.).
XX
SQ MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAA
SQ VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL
SQ NKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGS
SQ GEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFK
SQ FSYSEINFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQ
SQ QQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPP
SQ PVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDS
SQ LKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHV
SQ PPQGGTHRPPAPARIADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSA
SQ GYNRPAHHMVPRPSVPPPGANEEIPDDFDWDLIT
XX
SC translated from EMBL #AF155132
XX
FT 5 20 
conserved domain (I) in some forkhead factors [1].
FT 64 164 
fork head domain [1].
FT 64 153 
SM00339; forkneu4.
FT 66 143 
PS50039; FORK_HEAD_3.
FT 66 175 
PF00250; Fork head domain.
FT 150 156 
conserved domain (II) in some forkhead factors [1].
FT 513 574 
replaced with 513-526 in short isoform T04171 [2].
XX
SF binds to two different types of sequences, so FOXJ2 may bind DNA in two different independent manners [1];
SF two splice variants: one long and one short T04171 isoform which differ in expression level and transcriptional activation potential [2];
XX
CP (fetus:) liver [1], (adult:) spleen, thymus, prostate, testis, ovary, small intestine, colon, leukocytes, heart, brain, placenta, lung, liver, skel. muscle, kidney, pancreas, (cell lines:) NIN3T3, ES-2, Chang, C33, COS, HeLa, Hep3B, H5, UT-7 [2] [1] [2].
XX
FF transcriptional activator [1] [2];
FF may be involved in early development [1];
XX
MX M00422 V$FOXJ2_01.
MX M00423 V$FOXJ2_02.
XX
BS R09747.
BS R09748.
BS R09749.
BS R09750.
BS R09751.
BS R09752.
BS R09753.
BS R09754.
BS R09755.
BS R09756.
BS R09757.
BS R09758.
BS R09759.
BS R09760.
BS R09761.
BS R09762.
BS R09763.
BS R09764.
BS R09765.
BS R09766.
BS R09767.
BS R09768.
BS R09769.
BS R09770.
BS R09771.
BS R09772.
BS R09773.
BS R09774.
BS R09775.
BS R09776.
BS R09777.
BS R09778.
BS R09779.
BS R09780.
BS R09781.
BS R09782.
BS R09783.
BS R09784.
BS R09785.
BS R09786.
BS R09787.
BS R09788.
BS R09789.
BS R09790.
BS R09791.
BS R09792.
BS R09793.
BS R09746.
XX
DR TRANSPATH: MO000028062.
DR EMBL: AF155132;
DR UniProtKB: Q9P0K8-1;
XX
RN [1]; RE0015563.
RX PUBMED: 10777590.
RA Perez-Sanchez C., Gomez-Ferreria M. A., de La Fuente C. A., Granadino B., Velasco G., Esteban-Gamboa A., Rey-Campos J.
RT FHX, a novel fork head factor with a dual DNA binding specificity
RL J. Biol. Chem. 275:12909-12916 (2000).
RN [2]; RE0015566.
RX PUBMED: 10966786.
RA Perez-Sanchez C., Arias-de-la-Fuente C., Gomez-Ferreria M. A., Granadino B., Rey-Campos J.
RT FHX.L and FHX.S, two isoforms of the human fork-head factor FHX (FOXJ2) with differential activity
RL J. Mol. Biol. 301:795-806 (2000).
XX
//