AC T04215
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ID T04215
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DT 23.01.2001 (created); dkl.
DT 06.08.2014 (updated); hna.
CO Copyright (C), QIAGEN.
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FA Smad8
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SY Smad-8.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002406 Smad9.
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CL C0041; SMAD; 7.1.1.1.5.
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FF constitutively active ALK-2, ALK-3 and ALK-6 (BMP type I receptors) induce both phosphorylation and heterodimerization with Smad4 [1];
FF ALK-2 responding to BMP-7 and OP-1, ALK-3 and ALK-6 responding to BMP2 and BMP4 [1];
FF translocation to the nucleus is activated by BMP type I receptors [1];
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IN T05067 Smad4; mouse, Mus musculus.
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MX M08897 V$SMAD_Q4.
MX M00974 V$SMAD_Q6_01.
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BS R71669.
BS R32807.
BS R32808.
BS R63126.
BS R63127.
BS R63147.
BS R63149.
BS R63150.
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DR TRANSPATH: MO000020388.
DR UniProtKB: Q9JIW5; Q9JIW5.
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RN [1]; RE0015606.
RX PUBMED: 10814522.
RA Kawai S., Faucheu C., Gallea S., Spinella-Jaegle S., Atfi A., Baron R., Roman S. R.
RT Mouse smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity
RL Biochem. Biophys. Res. Commun. 271:682-687 (2000).
RN [2]; RE0054287.
RX PUBMED: 18039466.
RA Kochupurakkal B. S., Sarig R., Fuchs O., Piestun D., Rechavi G., Givol D.
RT Nanog inhibits the switch of myogenic cells towards the osteogenic lineage.
RL Biochem. Biophys. Res. Commun. 365:846-850 (2008).
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