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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T04237 XX ID T04237 XX DT 25.01.2001 (created); mpr. DT 21.05.2010 (updated); pum. CO Copyright (C), QIAGEN. XX FA zic2 XX SY zinc finger protein of the cerebellum 2; zinc finger protein zic2. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004028 ZIC2; HGNC: ZIC2. XX HO zic2 (Drosophila melanogaster). XX CL C0001; CH; 2.3.3.1.8. XX FF zic2 is predicted to contribute to the transcriptional activity of the apolipoprotein E gene [2]; FF heterozygous mutations in zic2 are associated with holoprosencephaly [1]; XX MX M07292 V$GLI_Q3. MX M00449 V$ZIC2_01. XX DR TRANSPATH: MO000028116. DR PATHODB: MT010683. DR PATHODB: MT010684. DR PATHODB: MT010685. DR PATHODB: MT010686. DR UniProtKB: O95409; XX RN [1]; RE0015621. RX PUBMED: 9771712. RA Brown S. A., Warburton D., Brown L. Y., Yu C.-Y., Roeder E. R., Stengel-Rutkowski S., Hennekam R. C. M., Muenke M. RT Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired RL Nat. Genet. 20:180-183 (1998). RN [2]; RE0015653. RX PUBMED: 11038359. RA Salero E., Perez-Sen R., Aruga J., Gimenez C., Zafra F. RT Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter RL J. Biol. Chem. 276:1881-1888 (2001). XX //