AC T04237
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ID T04237
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DT 25.01.2001 (created); mpr.
DT 21.05.2010 (updated); pum.
CO Copyright (C), QIAGEN.
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FA zic2
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SY zinc finger protein of the cerebellum 2; zinc finger protein zic2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004028 ZIC2; HGNC: ZIC2.
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HO zic2 (Drosophila melanogaster).
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CL C0001; CH; 2.3.3.1.8.
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FF zic2 is predicted to contribute to the transcriptional activity of the apolipoprotein E gene [2];
FF heterozygous mutations in zic2 are associated with holoprosencephaly [1];
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MX M07292 V$GLI_Q3.
MX M00449 V$ZIC2_01.
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DR TRANSPATH: MO000028116.
DR PATHODB: MT010683.
DR PATHODB: MT010684.
DR PATHODB: MT010685.
DR PATHODB: MT010686.
DR UniProtKB: O95409;
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RN [1]; RE0015621.
RX PUBMED: 9771712.
RA Brown S. A., Warburton D., Brown L. Y., Yu C.-Y., Roeder E. R., Stengel-Rutkowski S., Hennekam R. C. M., Muenke M.
RT Holoprosencephaly due to mutations in ZIC2, a homologue of Drosophila odd-paired
RL Nat. Genet. 20:180-183 (1998).
RN [2]; RE0015653.
RX PUBMED: 11038359.
RA Salero E., Perez-Sen R., Aruga J., Gimenez C., Zafra F.
RT Transcription factors Zic1 and Zic2 bind and transactivate the apolipoprotein E gene promoter
RL J. Biol. Chem. 276:1881-1888 (2001).
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