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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T04238 XX ID T04238 XX DT 25.01.2001 (created); dkl. DT 10.12.2009 (updated); ada. CO Copyright (C), QIAGEN. XX FA Smad8 XX SY Smad-8. XX OS rat, Rattus norvegicus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G002372 Smad9. XX CL C0041; SMAD; 7.1.1.1.5. XX SF NLS (Nuclear Localization Signal) determines the ligand-induced nuclear translocation [2]; XX FF Smad8 activates Xbra in animal pole explants [1]; FF ALK-2 phosphorylates Smad8 [1]; FF Smad8 cooperates with Smad4 [1]; XX IN T04292 Smad4; human, Homo sapiens. XX MX M08897 V$SMAD_Q4. MX M00974 V$SMAD_Q6_01. XX DR TRANSPATH: MO000020637. DR UniProtKB: O54835; O54835. XX RN [1]; RE0015643. RX PUBMED: 9371779. RA Chen Y., Bhushan A., Vale W. RT Smad8 mediates the signaling of the ALK-2 (corrected) receptor serine kinase RL Proc. Natl. Acad. Sci. USA 94:12938-12943 (1997). RN [2]; RE0016203. RX PUBMED: 10884415. RA Xiao Z., Liu X., Henis Y. I., Lodish H. F. RT A distinct nuclear localization signal in the N terminus of Smad 3 determines its ligand-induced nuclear translocation. RL Proc. Natl. Acad. Sci. USA 97:7853-7858 (2000). XX //