AC T04424
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ID T04424
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DT 17.04.2001 (created); rio.
DT 28.10.2015 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA Tbx20
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SY T-box protein 12; T-box protein 20; Tbx12.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002446 Tbx20.
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HO H15 T04412 (Dros.), tbx-12 T04410 (C. elegans).
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CL C0044; T-box; 6.5.3.0.5.
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SF most similar to Drosophila H15 T04412 [3];
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CP (E7.25-E8:) extraembryonic mesoderm, amnion, chorion, cardiogenic mesoderm, cardiogenic crescent, (E8.5-9.5:) looping heart tube, optic vesicle, hindbrain, rhombomeres r2, r4, r7 and r8, cervical spinal cord, (E7.75-10.5:) allantois, (E9.5:) paired ventrolateral regions of neural tube - probably motoneurons, forming heart, (E10.5:) segmental nerves lateral to the midline dorsal aorta, liver lobes, cells surrounding the aorta in the urogenital system, mantle region of ventral neural tube, (E10.5-11.5:) optic cup, periphery of neural retina, limb bud mesenchyme, maxillary and mandibular face mesenchyme, (E11.5:) umbilical cord, neural retina, (E9.5-15.5:) heart, endocardial cushion, outflow tract, myocardium, (adult:) neural retina, pigment epithelium, optic nerve [1] [2] [3].
CN (E9.5-15.5:) trabeculated region of ventricular myocardium [2].
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FF widespread early expression and more restricted later expression in the heart suggests that Tbx20 could play two distinct roles in heart development [3];
FF may have a role in limb and heart morphogenesis [2];
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MX M05458 V$TBX20_03.
MX M07474 V$TBX20_05.
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BS R70188.
BS R70189.
BS R70190.
BS R70191.
BS R70192.
BS R70193.
BS R70194.
BS R70195.
BS R70185.
BS R70196.
BS R70197.
BS R70198.
BS R70199.
BS R70200.
BS R70201.
BS R70202.
BS R70203.
BS R70204.
BS R70205.
BS R70206.
BS R70207.
BS R70208.
BS R69902.
BS R63716.
BS R69896.
BS R69898.
BS R69899.
BS R69895.
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DR TRANSPATH: MO000028278.
DR UniProtKB: Q9ES03;
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RN [1]; RE0016031.
RX PUBMED: 11118890.
RA Kraus F., Haenig B., Kispert A.
RT Cloning and expression analysis of the mouse T-box gene Tbx20
RL Mech. Dev. 100:87-91 (2001).
RN [2]; RE0016032.
RX PUBMED: 10936053.
RA Meins M., Henderson D. J., Bhattacharya S. S., Sowden J. C.
RT Characterization of the human TBX20 gene, a new member of the T-Box gene family closely related to the Drosophila H15 gene
RL Genomics 67:317-332 (2000).
RN [3]; RE0016057.
RX PUBMED: 10940636.
RA Carson C. T., Kinzler E. R., Parr B. A.
RT Tbx12, a novel T-box gene, is expressed during early stages of heart and retinal development
RL Mech. Dev. 96:137-140 (2000).
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