AC T05071
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ID T05071
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DT 19.03.2002 (created); mas.
DT 06.05.2009 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA gmeb2
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SY glucocorticoid modulatory element binding protein-2; GMEB2.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014444 Gmeb2.
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CL C0077; SAND; 5.3.3.1.2.
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SF at least 2 isoforms exist (sequence of longer one shown here) which probably result from alternative splicing [4];
SF contains a KDWK (KDWKR) sequence (pos. 139-143) which is also found in other transcription factors like human and rat Suppressin and drosophila DEAF-1 [4];
SF experimentally determined MW (67 kDa) higher than calculated MW (56.6 kDa) [4];
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FF repressor with no obvious dependency on binding to a specific DNA-sequence [3];
FF component of a complex of higher molecular mass (550 kDa) that binds to TAT gene G000798 upstream element GME R12323 and that also contains GMEB-1 T05072 [1];
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IN T05070 GMEB-1; mouse, Mus musculus.
IN T05072 GMEB-1; rat, Rattus norvegicus.
IN T05071 gmeb2; rat, Rattus norvegicus.
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DR TRANSPATH: MO000031262.
DR UniProtKB: O88873;
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RN [1]; RE0011313.
RX PUBMED: 7665613.
RA Oshima H., Szapary D., Simons S. S.
RT The factor binding of the glucocorticoid modulatory element of the tyrosine aminotransferase gene is a novel and ubiquitous heteromeric complex
RL J. Biol. Chem. 270:21893-21901 (1995).
RN [2]; RE0017627.
RX PUBMED: 10386584.
RA Theriault J. R., Charette S. J., Lambert H., Landry J.
RT Cloning and characterization of hGMEB1, a novel glucocorticoid modulatory element binding protein
RL FEBS Lett. 452:170-176 (1999).
RN [3]; RE0017628.
RX PUBMED: 10692587.
RA Jimenez-Lara A. M., Heine M. J., Gronemeyer H.
RT Cloning of a mouse glucocorticoid modulatory element binding protein, a new member of the KDWK family
RL FEBS Lett. 468:203-210 (2000).
RN [4]; RE0017630.
RX PUBMED: 9651376.
RA Zeng H., Jackson D. A., Oshima H., Simons SS J. r.
RT Cloning and characterization of a novel binding factor (GMEB-2) of the glucocorticoid modulatory element.
RL J. Biol. Chem. 273:17756-17762 (1998).
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